LOPRESTI, LUDOVICA
LOPRESTI, LUDOVICA
Dipartimento di Scienze della Vita
A novel class of oxazepine-based anti-cancer agents induces cell death in primary human CLL cells and efficiently reduces tumor growth in Eμ-TCL1 mice through the JNK/STAT4/p66Shc axis
2021-01-01 Vanni, Francesca; Lopresti, Ludovica; Zurli, Vanessa; Kabanova, Anna; Cattaneo, Francesca; Sicuranza, Anna; Gozzetti, Alessandro; Gemma, Sandra; Zisterer, Daniela M; Bocchia, Monica; Campiani, Giuseppe; Baldari, Cosima T; Butini, Stefania; Ulivieri, Cristina
A novel potent class I HDAC inhibitor reverses the STAT4/p66Shc apoptotic defect in B cells from chronic lymphocytic leukemia patients
2024-01-01 Rossi, Sara; Tatangelo, Vanessa; Dichiara, Maria; Butini, Stefania; Gemma, Sandra; Brogi, Simone; Pasquini, Silvia; Cappello, Martina; Vincenzi, Fabrizio; Varani, Katia; Lopresti, Ludovica; Malchiodi, Margherita; Carrara, Chiara; Gozzetti, Alessandro; Bocchia, Monica; Marotta, Giuseppe; Patrussi, Laura; Carullo, Gabriele; Baldari, Cosima T.; Campiani, Giuseppe
Evidence of destabilization of the human thymidylate synthase (hTS) dimeric structure induced by the interface mutation Q62R
2019-01-01 Pozzi, Cecilia; Lopresti, Ludovica; Santucci, Matteo; Costi, Maria Paola; Mangani, Stefano
Leukemic cell-secreted interleukin-9 suppresses cytotoxic T cell-mediated killing in chronic lymphocytic leukemia
2024-01-01 Boncompagni, Gioia; Tatangelo, Vanessa; Lopresti, Ludovica; Ulivieri, Cristina; Capitani, Nagaja; Tangredi, Carmela; Finetti, Francesca; Marotta, Giuseppe; Frezzato, Federica; Visentin, Andrea; Ciofini, Sara; Gozzetti, Alessandro; Bocchia, Monica; Calzada-Fraile, Diego; Martin Cofreces, Noa B.; Trentin, Livio; Patrussi, Laura; Baldari, Cosima T.
p66Shc Deficiency in Chronic Lymphocytic Leukemia Promotes Chemokine Receptor Expression Through the ROS-Dependent Inhibition of NF-κB
2022-01-01 Tatangelo, Vanessa; Boncompagni, Gioia; Capitani, Nagaja; Lopresti, Ludovica; Manganaro, Noemi; Frezzato, Federica; Visentin, Andrea; Trentin, Livio; Baldari, Cosima; Patrussi, Laura
p66Shc deficiency in CLL cells enhances PD-L1 expression and suppresses immune synapse formation
2024-01-01 Lopresti, Ludovica; Capitani, Nagaja; Tatangelo, Vanessa; Tangredi, Carmela; Boncompagni, Gioia; Frezzato, Federica; Visentin, Andrea; Marotta, Giuseppe; Ciofini, Sara; Gozzetti, Alessandro; Bocchia, Monica; Trentin, Livio; Baldari, Cosima; Patrussi, Laura
Rewiring the T cell-suppressive cytokine landscape of the tumor microenvironment: a new frontier for precision anti-cancer therapy
2024-01-01 Lopresti, Ludovica; Tatangelo, Vanessa; Baldari, Cosima T.; Patrussi, Laura
Structural and functional characterization of new human thymidylate synthase interface variants
2019-01-01 Lopresti, Ludovica; Pozzi, Cecilia; Santucci, Matteo; Paola Costi, Maria; Mangani, Stefano
Structural and functional characterization of new human thymidylate synthase interface variants
2019-01-01 Lopresti, L; Pozzi, C; Santucci, M; Costi, Mp; Mangani, S
STRUCTURAL AND FUNCTIONAL STUDIES ON PROTEINS RELATED TO HUMAN DISEASES
2022-01-01 Lopresti, Ludovica
Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents
2019-01-01 Brindisi, Margherita; Ulivieri, Cristina; Alfano, Gloria; Gemma, Sandra; de Asís Balaguer, Francisco; Khan, Tuhina; Grillo, Alessandro; Chemi, Giulia; Menchon, Grégory; Prota, Andrea E; Olieric, Natacha; Lucena-Agell, Daniel; Barasoain, Isabel; Diaz, J Fernando; Nebbioso, Angela; Conte, Mariarosaria; Lopresti, Ludovica; Magnano, Stefania; Amet, Rebecca; Kinsella, Paula; Zisterer, Daniela M; Ibrahim, Ola; O'Sullivan, Jeff; Morbidelli, Lucia; Spaccapelo, Roberta; Baldari, Cosima; Butini, Stefania; Novellino, Ettore; Campiani, Giuseppe; Altucci, Lucia; Steinmetz, Michel O; Brogi, Simone
Targeting Methyltransferases in Human Pathogenic Bacteria: Insights into Thymidylate Synthase (TS) and Flavin-Dependent TS (FDTS)
2019-01-01 Pozzi, Cecilia; Lopresti, Ludovica; Tassone, Giusy; Mangani, Stefano
Targeting Methyltransferases in Human Pathogenic Bacteria: Insights into Thymidylate Synthase (TS) and Flavin-Dependent TS (FDTS)
2019-01-01 Pozzi, Cecilia; Lopresti, Ludovica; Tassone, Giusy; Mangani, Stefano
Unravelling the response of chronic lymphocytic leukemia to a novel class of anticancer agents, the pyrrolonaphthoxazepines (PNOXs)
2019-01-01 Vanni, Francesca; Lopresti, Ludovica; Khan, Tuhina; Zisterer, Daniela M.; Francesca, Cattaneo1; Zurli, Vanessa; Kabanova, Anna; Bocchia, Monica; Campiani, Giuseppe; Baldari, Cosima T.; Butini, Stefania; Ulivieri, Cristina
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| A novel class of oxazepine-based anti-cancer agents induces cell death in primary human CLL cells and efficiently reduces tumor growth in Eμ-TCL1 mice through the JNK/STAT4/p66Shc axis | 1-gen-2021 | Vanni, Francesca; Lopresti, Ludovica; Zurli, Vanessa; Kabanova, Anna; Cattaneo, Francesca; Sicuranza, Anna; Gozzetti, Alessandro; Gemma, Sandra; Zisterer, Daniela M; Bocchia, Monica; Campiani, Giuseppe; Baldari, Cosima T; Butini, Stefania; Ulivieri, Cristina | - | |
| A novel potent class I HDAC inhibitor reverses the STAT4/p66Shc apoptotic defect in B cells from chronic lymphocytic leukemia patients | 1-gen-2024 | Rossi, Sara; Tatangelo, Vanessa; Dichiara, Maria; Butini, Stefania; Gemma, Sandra; Brogi, Simone; Pasquini, Silvia; Cappello, Martina; Vincenzi, Fabrizio; Varani, Katia; Lopresti, Ludovica; Malchiodi, Margherita; Carrara, Chiara; Gozzetti, Alessandro; Bocchia, Monica; Marotta, Giuseppe; Patrussi, Laura; Carullo, Gabriele; Baldari, Cosima T.; Campiani, Giuseppe | - | |
| Evidence of destabilization of the human thymidylate synthase (hTS) dimeric structure induced by the interface mutation Q62R | 1-gen-2019 | Pozzi, Cecilia; Lopresti, Ludovica; Santucci, Matteo; Costi, Maria Paola; Mangani, Stefano | - | |
| Leukemic cell-secreted interleukin-9 suppresses cytotoxic T cell-mediated killing in chronic lymphocytic leukemia | 1-gen-2024 | Boncompagni, Gioia; Tatangelo, Vanessa; Lopresti, Ludovica; Ulivieri, Cristina; Capitani, Nagaja; Tangredi, Carmela; Finetti, Francesca; Marotta, Giuseppe; Frezzato, Federica; Visentin, Andrea; Ciofini, Sara; Gozzetti, Alessandro; Bocchia, Monica; Calzada-Fraile, Diego; Martin Cofreces, Noa B.; Trentin, Livio; Patrussi, Laura; Baldari, Cosima T. | - | |
| p66Shc Deficiency in Chronic Lymphocytic Leukemia Promotes Chemokine Receptor Expression Through the ROS-Dependent Inhibition of NF-κB | 1-gen-2022 | Tatangelo, Vanessa; Boncompagni, Gioia; Capitani, Nagaja; Lopresti, Ludovica; Manganaro, Noemi; Frezzato, Federica; Visentin, Andrea; Trentin, Livio; Baldari, Cosima; Patrussi, Laura | - | |
| p66Shc deficiency in CLL cells enhances PD-L1 expression and suppresses immune synapse formation | 1-gen-2024 | Lopresti, Ludovica; Capitani, Nagaja; Tatangelo, Vanessa; Tangredi, Carmela; Boncompagni, Gioia; Frezzato, Federica; Visentin, Andrea; Marotta, Giuseppe; Ciofini, Sara; Gozzetti, Alessandro; Bocchia, Monica; Trentin, Livio; Baldari, Cosima; Patrussi, Laura | - | |
| Rewiring the T cell-suppressive cytokine landscape of the tumor microenvironment: a new frontier for precision anti-cancer therapy | 1-gen-2024 | Lopresti, Ludovica; Tatangelo, Vanessa; Baldari, Cosima T.; Patrussi, Laura | - | |
| Structural and functional characterization of new human thymidylate synthase interface variants | 1-gen-2019 | Lopresti, Ludovica; Pozzi, Cecilia; Santucci, Matteo; Paola Costi, Maria; Mangani, Stefano | - | |
| Structural and functional characterization of new human thymidylate synthase interface variants | 1-gen-2019 | Lopresti, L; Pozzi, C; Santucci, M; Costi, Mp; Mangani, S | - | |
| STRUCTURAL AND FUNCTIONAL STUDIES ON PROTEINS RELATED TO HUMAN DISEASES | 1-gen-2022 | Lopresti, Ludovica | - | |
| Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents | 1-gen-2019 | Brindisi, Margherita; Ulivieri, Cristina; Alfano, Gloria; Gemma, Sandra; de Asís Balaguer, Francisco; Khan, Tuhina; Grillo, Alessandro; Chemi, Giulia; Menchon, Grégory; Prota, Andrea E; Olieric, Natacha; Lucena-Agell, Daniel; Barasoain, Isabel; Diaz, J Fernando; Nebbioso, Angela; Conte, Mariarosaria; Lopresti, Ludovica; Magnano, Stefania; Amet, Rebecca; Kinsella, Paula; Zisterer, Daniela M; Ibrahim, Ola; O'Sullivan, Jeff; Morbidelli, Lucia; Spaccapelo, Roberta; Baldari, Cosima; Butini, Stefania; Novellino, Ettore; Campiani, Giuseppe; Altucci, Lucia; Steinmetz, Michel O; Brogi, Simone | - | |
| Targeting Methyltransferases in Human Pathogenic Bacteria: Insights into Thymidylate Synthase (TS) and Flavin-Dependent TS (FDTS) | 1-gen-2019 | Pozzi, Cecilia; Lopresti, Ludovica; Tassone, Giusy; Mangani, Stefano | - | |
| Targeting Methyltransferases in Human Pathogenic Bacteria: Insights into Thymidylate Synthase (TS) and Flavin-Dependent TS (FDTS) | 1-gen-2019 | Pozzi, Cecilia; Lopresti, Ludovica; Tassone, Giusy; Mangani, Stefano | - | |
| Unravelling the response of chronic lymphocytic leukemia to a novel class of anticancer agents, the pyrrolonaphthoxazepines (PNOXs) | 1-gen-2019 | Vanni, Francesca; Lopresti, Ludovica; Khan, Tuhina; Zisterer, Daniela M.; Francesca, Cattaneo1; Zurli, Vanessa; Kabanova, Anna; Bocchia, Monica; Campiani, Giuseppe; Baldari, Cosima T.; Butini, Stefania; Ulivieri, Cristina | - |