Nome |
# |
Folate-targeted liposomal nitrooxy-doxorubicin: an effective tool against P-glycoprotein-positive and folate receptor-positive tumors, file e0feeaa6-c766-44d2-e053-6605fe0a8db0
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254
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From in silico to in vitro: A trip to reveal flavonoid binding on the Rattus norvegicus Kir6.1 ATP-sensitive inward rectifier potassium channel, file e0feeaa7-a8af-44d2-e053-6605fe0a8db0
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177
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null, file e0feeaa6-2b7e-44d2-e053-6605fe0a8db0
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145
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The selective rat toxicant norbormide blocks KATP channels in smooth muscle cells but not in insulin-secreting cells, file e0feeaa8-2cb5-44d2-e053-6605fe0a8db0
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99
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Hyaluronated liposomes containing H2S-releasing doxorubicin are effective against P-glycoprotein-positive/doxorubicin-resistant osteosarcoma cells and xenografts, file e0feeaab-985d-44d2-e053-6605fe0a8db0
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76
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Vascular toxicity risk assessment of MC18 and MC70, novel potential diagnostic tools for in vivo PET studies, file e0feeaa6-25fb-44d2-e053-6605fe0a8db0
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66
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Folate-targeted liposomal nitrooxy-doxorubicin: an effective tool against P-glycoprotein-positive and folate receptor-positive tumors, file e0feeaab-9c74-44d2-e053-6605fe0a8db0
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63
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The surge of flavonoids as novel, fine regulators of cardiovascular Cav channels, file e0feeaab-b27c-44d2-e053-6605fe0a8db0
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59
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null, file e0feeaaa-6854-44d2-e053-6605fe0a8db0
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40
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Vasorelaxant Effects Induced by Red Wine and Pomace Extracts of Magliocco Dolce cv, file e0feeaa9-0e62-44d2-e053-6605fe0a8db0
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33
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Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]- N -[(piperidin-4-yl)methyl]methanamine (MMV019918) and analogues, file e0feeaab-8d37-44d2-e053-6605fe0a8db0
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27
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Screening for potential hazard effects from multitarget anthracycline on the cardiovascular system, file e0feeaa6-27f5-44d2-e053-6605fe0a8db0
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26
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A Comprehensive Evaluation of Sdox, a Promising H2S-Releasing Doxorubicin for the Treatment of Chemoresistant Tumors, file e0feeaab-8bc8-44d2-e053-6605fe0a8db0
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22
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Selective Fatty Acid Amide Hydrolase Inhibitors as Potential Novel Antiepileptic Agents, file e0feeaaa-d08a-44d2-e053-6605fe0a8db0
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21
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Vasoactivity of Mantonico and Pecorello grape pomaces on rat aorta rings: An insight into nutraceutical development, file e0feeaab-7aaa-44d2-e053-6605fe0a8db0
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20
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Functional, electrophysiological and molecular docking analysis of the modulation of Cav 1.2 channels in rat vascular myocytes by murrayafoline A, file e0feeaab-569f-44d2-e053-6605fe0a8db0
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14
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Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain, file e0feeaab-8ed4-44d2-e053-6605fe0a8db0
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12
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Vietnamese Dalbergia tonkinensis: A Promising Source of Mono- and Bifunctional Vasodilators, file a3f38475-75b8-4606-a617-ac761515dd2f
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11
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Screening for potential hazardous effects of an H2S-donating anthracycline on the cardiovascular system., file e0feeaa6-c320-44d2-e053-6605fe0a8db0
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10
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Repurposing old drugs to fight multidrug resistant cancers, file e0feeaaa-dd9b-44d2-e053-6605fe0a8db0
|
10
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Wine Lees as Source of Antioxidant Molecules: Green Extraction Procedure and Biological Activity, file e3e40e32-45b5-485b-a5aa-07a224e55b30
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10
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Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]- N -[(piperidin-4-yl)methyl]methanamine (MMV019918) and analogues, file e0feeaa7-7f44-44d2-e053-6605fe0a8db0
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7
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2-hydroxy-4-(3,5,7-trihydroxy-4-oxo-4H-chromen-2-yl)phenyl(E)-3-(4-hydroxy-3-methoxyphenyl)acrylate: synthesis, in silico analysis and in vitro pharmacological evaluation, file e0feeaaa-b534-44d2-e053-6605fe0a8db0
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7
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Cancer cell permeability-glycoprotein as a target of MDR reverters: possible role of novel dihydropyridine derivatives, file e0feeaa4-dc32-44d2-e053-6605fe0a8db0
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6
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Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain, file e0feeaa7-68c7-44d2-e053-6605fe0a8db0
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6
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The beneficial health effects of flavonoids on the cardiovascular system: focus on K+ channels, file e0feeaa8-b00c-44d2-e053-6605fe0a8db0
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6
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Cancer cell permeability-glycoprotein as a target of MDR reverters: possible role of novel dihydropyridine derivatives, file e0feeaa4-e433-44d2-e053-6605fe0a8db0
|
5
|
Human Tuberculosis. III. Current and Prospective Approaches in Anti-Tubercular Therapy, file e0feeaa5-cd79-44d2-e053-6605fe0a8db0
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5
|
Negative chronotropism, positive inotropism and lusitropism of 3,5-di-t-butyl-4-hydroxyanisole (DTBHA) on rat heart preparations occur through reduction of RyR2 Ca2+ leak, file e0feeaa7-a2f0-44d2-e053-6605fe0a8db0
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5
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Hyaluronated liposomes containing H2S-releasing doxorubicin are effective against P-glycoprotein-positive/doxorubicin-resistant osteosarcoma cells and xenografts, file e0feeaa8-1161-44d2-e053-6605fe0a8db0
|
5
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Antihypertensive, cardio-and neuroprotective effects of Tenebrio molitor (Coleoptera: Tenebrionidae) defatted larvae in spontaneously hypertensive rats, file e0feeaa9-324f-44d2-e053-6605fe0a8db0
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5
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Vasoactivity of Mantonico and Pecorello grape pomaces on rat aorta rings: An insight into nutraceutical development, file e0feeaa8-3538-44d2-e053-6605fe0a8db0
|
4
|
Sdox, a H2S releasing anthracycline, with a safer profile than doxorubicin toward vasculature, file e0feeaab-8c43-44d2-e053-6605fe0a8db0
|
4
|
Sdox, a H2S releasing anthracycline, with a safer profile than doxorubicin toward vasculature, file 456fc7f9-2d99-4791-b540-b60e6ff4eae9
|
3
|
null, file e0feeaa5-790f-44d2-e053-6605fe0a8db0
|
3
|
Functional, electrophysiological and molecular docking analysis of the modulation of Cav 1.2 channels in rat vascular myocytes by murrayafoline A, file e0feeaa5-7e72-44d2-e053-6605fe0a8db0
|
3
|
Vascular Toxicity Risk Assessment of MC18 and MC70, Novel Potential Diagnostic Tools for In Vivo PET Studies, file e0feeaa6-249b-44d2-e053-6605fe0a8db0
|
3
|
The surge of flavonoids as novel, fine regulators of cardiovascular Cav channels, file e0feeaa6-2675-44d2-e053-6605fe0a8db0
|
3
|
In vitro assessement of tariquidar toxicity towards vasculature, file e0feeaa6-2f2c-44d2-e053-6605fe0a8db0
|
3
|
New NO- and H2S-releasing doxorubicins as targeted therapy against chemoresistance in castration-resistant prostate cancer: in vitro and in vivo evaluations, file e0feeaa7-ee5a-44d2-e053-6605fe0a8db0
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3
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A multitarget semi-synthetic derivative of the flavonoid morin with improved in vitro vasorelaxant activity: Role of CaV1.2 and KCa1.1 channels, file e0feeaaa-1977-44d2-e053-6605fe0a8db0
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3
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null, file 255b053e-58f6-4f61-a12e-67a3bea3b86d
|
2
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null, file c5da9a26-56df-4df2-b01d-174bf8a6f71e
|
2
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Understanding Oxadiazolothiazinone Biological Properties: Negative Inotropic Activity versus Cytochrome P450-Mediated Metabolism, file e0feeaa5-de66-44d2-e053-6605fe0a8db0
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2
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null, file e0feeaa5-e2fc-44d2-e053-6605fe0a8db0
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2
|
Mitochondrial-targeting nitrooxy-doxorubicin: effects on P-glycoprotein and assessment of their vascular effects, file e0feeaa6-2680-44d2-e053-6605fe0a8db0
|
2
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The multi-factorial nature of clinical multidrug resistance in cancer, file e0feeaa8-43a9-44d2-e053-6605fe0a8db0
|
2
|
Ritanserin blocks CaV1.2 channels in rat artery smooth muscles: electrophysiological, functional, and computational studies, file e0feeaa9-830a-44d2-e053-6605fe0a8db0
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2
|
Design, synthesis and pharmacological evaluation of ester-based quercetin derivatives as selective vascular KCa1.1 channel stimulators, file e0feeaa9-83e9-44d2-e053-6605fe0a8db0
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2
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Flavonoids and hERG channels: Friends or foes?, file e0feeaa9-c840-44d2-e053-6605fe0a8db0
|
2
|
Harnessing the Role of HDAC6 in Idiopathic Pulmonary Fibrosis: Design, Synthesis, Structural Analysis, and Biological Evaluation of Potent Inhibitors, file e0feeaaa-274a-44d2-e053-6605fe0a8db0
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2
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Off-label use of hydroxychloroquine in COVID-19: analysis of reports of suspected adverse reactions from the Italian National Network of Pharmacovigilance, file 804b1f0a-3297-41ef-99c5-dd22d361a750
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1
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Novel Labdane Diterpenes-Based Synthetic Derivatives: Identification of a Bifunctional Vasodilator That Inhibits CaV1.2 and Stimulates KCa1.1 Channels, file aa2879c2-dcbb-4ade-96d4-3fc402116e63
|
1
|
The novel potent multidrug resistance inhibitors N,N-bis(cyclohexanol)amine aryl esters are devoid of vascular effects, file e0feeaa4-dae3-44d2-e053-6605fe0a8db0
|
1
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Cardamonin is a bifunctional vasodilator that inhibits Cav1.2 current and stimulates KCa1.1 current in rat tail artery myocytes, file e0feeaa4-dfab-44d2-e053-6605fe0a8db0
|
1
|
A specific taurine recognition site in the rabbit brain is responsible for taurine effects on thermoregulation., file e0feeaa4-e046-44d2-e053-6605fe0a8db0
|
1
|
L-type Ca2+ channels activation and contraction elicited by myricetin on vascular smooth muscles., file e0feeaa4-e09b-44d2-e053-6605fe0a8db0
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1
|
3,5-dibenzoyl-4-(3-phenoxyphenyl)-1,4-dihydro-2,6-dimethylpyridine (DP7): a new multidrug resistance inhibitor devoid of effects on Langendorff-perfused rat heart., file e0feeaa4-e857-44d2-e053-6605fe0a8db0
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1
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null, file e0feeaa5-e749-44d2-e053-6605fe0a8db0
|
1
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In vitro vascular toxicity of tariquidar, a potential tool for in vivo PET studies, file e0feeaa6-971c-44d2-e053-6605fe0a8db0
|
1
|
Interference measurements and failure analysis of patch-clamp laboratory instrumentation for electrophysiology tests, file e0feeaa7-ba88-44d2-e053-6605fe0a8db0
|
1
|
In vitro vascular toxicity assessment of NitDOX, a novel NO-releasing doxorubicin, file e0feeaa9-5bc3-44d2-e053-6605fe0a8db0
|
1
|
Repurposing old drugs to fight multidrug resistant cancers, file e0feeaa9-6ad2-44d2-e053-6605fe0a8db0
|
1
|
MC225, a novel probe for P-glycoprotein PET Imaging at the blood-brain barrier: in vitro cardiovascular safety evaluation, file e0feeaa9-768c-44d2-e053-6605fe0a8db0
|
1
|
Proton pump inhibitors directly block hERG-potassium channel and independently increase the risk of QTc prolongation in a large cohort of US Veterans, file e0feeaaa-4660-44d2-e053-6605fe0a8db0
|
1
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Hypoxia as a driver of resistance to immunotherapy, file e0feeaab-6ee4-44d2-e053-6605fe0a8db0
|
1
|
Nitrobenzoxadiazole derivatives of the rat selective toxicant norbormide as fluorescent probes for live cell imaging, file e0feeaab-8c40-44d2-e053-6605fe0a8db0
|
1
|
Totale |
1320 |