Sfoglia per Autore
Neuronal high affinity sodium-dependent glutamate transporters (EAATs): targets for the development of novel therapeutics against neurodegenerative diseases
2003-01-01 Campiani, G.; Fattorusso, C.; DE ANGELIS, M.; Catalanotti, B.; Butini, S.; Fattorusso, R.; Fiorini, I.; Nacci, V.; Novellino, E.
Synthesis of new molecular probes for investigation of steroid biosynthesis induced by selective interaction with peripheral-type benzodiazepine receptors (PBR)
2002-01-01 Campiani, G.; Ramunno, A.; Fiorini, I.; Nacci, V.; Morelli, E.; Novellino, E.; Goegan, M.; Mennini, T.; Sullivan, S.; Zisterer, D. M.; Williams, C. D.
Polycondensed heterocycles. X. A new method for the preparation of pyrrolo[2,1-c][1,4]benzothiazepines by intramolecular mitsunobu cyclisation
1999-01-01 Garofalo, Antonio; Campiani, Giuseppe; Fiorini, Isabella; Nacci, Vito
Thiazolothiazepine Inhibitors of HIV-1 Integrase
1999-01-01 Neamati, N.; Turpin, J. A.; Winslow, H. E.; Christensen, J. L.; Williamson, K.; Orr, A.; Rice, W. G.; Pommier, Y.; Garofalo, A.; Brizzi, A.; Campiani, G.; Fiorini, I.; Nacci, V.
New Antipsychotic Agents with Serotonin and Dopamine Antagonist Properties Based on a Pyrrolo[2,1-b][1,3]benzothiazepine Structure
1998-01-01 Campiani, Giuseppe; Nacci, Vito; Bechelli, Susanna; Ciani, Silvia M.; Garofalo, Antonio; Fiorini, Isabella; Wikström, Håkan; De Boer, Peter; Liao, Yi; Tepper, Pieter G.; Cagnotto, Alfredo; Mennini, Tiziana
New pyrrolobenzothiazepine derivatives as molecular probes of the ‘peripheral-type’ benzodiazepine receptor (PBR) binding site
1997-01-01 Campiani, G.; Nacci, V.; Fiorini, I.; De Filippis, M. P.; Garofalo, A.; Ciani, S. M.; Greco, G.; Novellino, E.; Manzoni, C.; Mennini, T.
Pyrrolobenzothiazepinones and Pyrrolobenzoxazepinones: Novel and Specific Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors with Antiviral Activity
1996-01-01 Campiani, Giuseppe; Nacci, Vito; Fiorini, Isabella; De Filippis, Maria P.; Garofalo, Antonio; Greco, Giovanni; Novellino, Ettore; Altamura, Sergio; Di Renzo, Laura
Synthesis, Biological Activity, and SARs of Pyrrolobenzoxazepine Derivatives, a New Class of Specific “Peripheral-Type” Benzodiazepine Receptor Ligands
1996-01-01 Campiani, Giuseppe; Nacci, Vito; Fiorini, Isabella; De Filippis, Maria P.; Garofalo, Antonio; Ciani, Silvia M.; Greco, Giovanni; Novellino, Ettore; Williams, D. Clive; Zisterer, Daniela M.; Woods, Margaret J.; Mihai, Camelia
Cardiovascular Characterization of Pyrrolo[2,1-d][1,5]benzothiazepine Derivatives Binding Selectively to the Peripheral-Type Benzodiazepine Receptor (PBR): From Dual PBR Affinity and Calcium Antagonist Activity to Novel and Selective Calcium Entry Blockers
1996-01-01 Campiani, Giuseppe; Fiorini, Isabella; De Filippis, Maria P.; Ciani, Silvia M.; Garofalo, Antonio; Nacci, Vito; Giorgi, Gianluca; Sega, Alessandro; Botta, Maurizio; Chiarini, Alberto; Budriesi, Roberta; Bruni, Giancarlo
Polycondensed heterocycles. IX. Pyrrolo[2,1-c][1,4]benzothiazepines. Synthesis of 3-(dimethylamino)methyl derivatives
1996-01-01 Garofalo, Antonio; Campiani, Giuseppe; Ciani, Silvia M.; Fiorini, Isabella; Nacci, Vito
A Concerted Study Using Binding Measurements, X-ray Structural Data, and Molecular Modeling on the Stereochemical Features Responsible for the Affinity of 6-Arylpyrrolo[2,1-d][1,5]benzothiazepines toward Mitochondrial Benzodiazepine Receptors
1995-01-01 Dalpiaz, Alessandro; Bertolasi, Valerio; Boreal, Pier Andrea; Nacci, Vito; Fiorini, Isabella; Campiani, Giuseppe; Mennini, Tiziana; Manzoni, Cristina; Novellino, Ettore; Greco, Giovanni
Pyrrolo[2,1-c][1,4]benzothiazines: Synthesis, Structure-Activity Relationships, Molecular Modeling Studies, and Cardiovascular Activity
1995-01-01 Campiani, Giuseppe; Garofalo, Antonio; Fiorini, Isabella; Botta, Maurizio; Nacci, Vito; Tafi, Andrea; Chiarini, Alberto; Budriesi, Roberta; Bruni, Giancarlo; Romeo, Maria R. c
Novel Ligands Specific for Mitochondrial Benzodiazepine Receptors: 6-arylpyrrolo[2,1-d][1,5]benzothiazepine Derivatives. Synthesis, Structure-Activity Relationships, and Molecular Modeling Studies
1994-01-01 Fiorini, Isabella; Nacci, Vito; Ciani, Silvia Maria; Garofalo, Antonio; Campiani, Giuseppe; Savini, Luisa; Novellino, Ettore; Greco, Gianni; Bernasconi, Paola; Mennini, Tiziana
Synthesis and “in vitro” cardiovascular activity of 4-aryl-2,3,3a,4-tetrahydro-1h-pyrrolo[2,1-c][1,4]benzothiazin-1-ones and 7-acetoxy-6-phenyl-7a,8,9,10-tetrahydropyrrolo [2,1,-d][1,5]benzothiazepin-10-one
1994-01-01 Campiani, G.; Garofalo, A.; Fiorini, I.; Nacci, V.; Botta, M.; Tafi, A.; Chiarini, A.; Budriesi, R.; Bruni, G.; Romeo, M. R.
A Comparative Molecular Field Analysis Model for 6-Arylpyrrolo[2,1-d][1,5]benzothiazepines Binding Selectively to the Mitochondrial Benzodiazepine Receptor
1994-01-01 Greco, Giovanni; Novellino, Ettore; Fiorini, Isabella; Nacci, Vito; Campiani, Giuseppe; Ciani, Silvia M.; Garofalo, Antonio; Bernasconi, Paola; Mennini, Tiziana
Benzothiazine and Benzothiazepine derivatives: synthesis and preliminary biological evaluation
1993-01-01 Garofalo, A.; Campiani, G.; Fiorini, I.; Nacci, V.
Pyrazolo[4,3-c]quinolines. Synthesis and specific inhibition of benzodiazepine receptor binding (Note I)
1993-01-01 Savini, Luisa; Massarelli, Paola; Pellerano, Cesare; Fiorini, Isabella; Bruni, Giancarlo; Romeo, M. R.
Synthesis and preliminary biological evaluation of 1-aminomethyl-4-substituted-4-H-pyrrolo[2,1-C][1,4] benzothiazines, a new class of calcium antagonists
1992-01-01 Campiani, G.; Nacci, V.; Garofalo, A.; Botta, M.; Fiorini, I.; Tafi, A.; Bruni, G.; Romeo, M. R.; Peres, A.; Bertollini, L.
Polycondensed heterocycles. VIII. Synthesis of 11-aryl-5H,11H-Pyrrolo[2,1-c][1,4]benzothiazepines by Pummerer rearrangement-cyclization reaction
1992-01-01 Garofalo, Antonio; Campiani, Giuseppe; Nacci, Vito; Fiorini, Isabella
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| Neuronal high affinity sodium-dependent glutamate transporters (EAATs): targets for the development of novel therapeutics against neurodegenerative diseases | 1-gen-2003 | Campiani, G.; Fattorusso, C.; DE ANGELIS, M.; Catalanotti, B.; Butini, S.; Fattorusso, R.; Fiorini, I.; Nacci, V.; Novellino, E. | - | |
| Synthesis of new molecular probes for investigation of steroid biosynthesis induced by selective interaction with peripheral-type benzodiazepine receptors (PBR) | 1-gen-2002 | Campiani, G.; Ramunno, A.; Fiorini, I.; Nacci, V.; Morelli, E.; Novellino, E.; Goegan, M.; Mennini, T.; Sullivan, S.; Zisterer, D. M.; Williams, C. D. | - | |
| Polycondensed heterocycles. X. A new method for the preparation of pyrrolo[2,1-c][1,4]benzothiazepines by intramolecular mitsunobu cyclisation | 1-gen-1999 | Garofalo, Antonio; Campiani, Giuseppe; Fiorini, Isabella; Nacci, Vito | - | |
| Thiazolothiazepine Inhibitors of HIV-1 Integrase | 1-gen-1999 | Neamati, N.; Turpin, J. A.; Winslow, H. E.; Christensen, J. L.; Williamson, K.; Orr, A.; Rice, W. G.; Pommier, Y.; Garofalo, A.; Brizzi, A.; Campiani, G.; Fiorini, I.; Nacci, V. | - | |
| New Antipsychotic Agents with Serotonin and Dopamine Antagonist Properties Based on a Pyrrolo[2,1-b][1,3]benzothiazepine Structure | 1-gen-1998 | Campiani, Giuseppe; Nacci, Vito; Bechelli, Susanna; Ciani, Silvia M.; Garofalo, Antonio; Fiorini, Isabella; Wikström, Håkan; De Boer, Peter; Liao, Yi; Tepper, Pieter G.; Cagnotto, Alfredo; Mennini, Tiziana | - | |
| New pyrrolobenzothiazepine derivatives as molecular probes of the ‘peripheral-type’ benzodiazepine receptor (PBR) binding site | 1-gen-1997 | Campiani, G.; Nacci, V.; Fiorini, I.; De Filippis, M. P.; Garofalo, A.; Ciani, S. M.; Greco, G.; Novellino, E.; Manzoni, C.; Mennini, T. | - | |
| Pyrrolobenzothiazepinones and Pyrrolobenzoxazepinones: Novel and Specific Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors with Antiviral Activity | 1-gen-1996 | Campiani, Giuseppe; Nacci, Vito; Fiorini, Isabella; De Filippis, Maria P.; Garofalo, Antonio; Greco, Giovanni; Novellino, Ettore; Altamura, Sergio; Di Renzo, Laura | - | |
| Synthesis, Biological Activity, and SARs of Pyrrolobenzoxazepine Derivatives, a New Class of Specific “Peripheral-Type” Benzodiazepine Receptor Ligands | 1-gen-1996 | Campiani, Giuseppe; Nacci, Vito; Fiorini, Isabella; De Filippis, Maria P.; Garofalo, Antonio; Ciani, Silvia M.; Greco, Giovanni; Novellino, Ettore; Williams, D. Clive; Zisterer, Daniela M.; Woods, Margaret J.; Mihai, Camelia | - | |
| Cardiovascular Characterization of Pyrrolo[2,1-d][1,5]benzothiazepine Derivatives Binding Selectively to the Peripheral-Type Benzodiazepine Receptor (PBR): From Dual PBR Affinity and Calcium Antagonist Activity to Novel and Selective Calcium Entry Blockers | 1-gen-1996 | Campiani, Giuseppe; Fiorini, Isabella; De Filippis, Maria P.; Ciani, Silvia M.; Garofalo, Antonio; Nacci, Vito; Giorgi, Gianluca; Sega, Alessandro; Botta, Maurizio; Chiarini, Alberto; Budriesi, Roberta; Bruni, Giancarlo | - | |
| Polycondensed heterocycles. IX. Pyrrolo[2,1-c][1,4]benzothiazepines. Synthesis of 3-(dimethylamino)methyl derivatives | 1-gen-1996 | Garofalo, Antonio; Campiani, Giuseppe; Ciani, Silvia M.; Fiorini, Isabella; Nacci, Vito | - | |
| A Concerted Study Using Binding Measurements, X-ray Structural Data, and Molecular Modeling on the Stereochemical Features Responsible for the Affinity of 6-Arylpyrrolo[2,1-d][1,5]benzothiazepines toward Mitochondrial Benzodiazepine Receptors | 1-gen-1995 | Dalpiaz, Alessandro; Bertolasi, Valerio; Boreal, Pier Andrea; Nacci, Vito; Fiorini, Isabella; Campiani, Giuseppe; Mennini, Tiziana; Manzoni, Cristina; Novellino, Ettore; Greco, Giovanni | - | |
| Pyrrolo[2,1-c][1,4]benzothiazines: Synthesis, Structure-Activity Relationships, Molecular Modeling Studies, and Cardiovascular Activity | 1-gen-1995 | Campiani, Giuseppe; Garofalo, Antonio; Fiorini, Isabella; Botta, Maurizio; Nacci, Vito; Tafi, Andrea; Chiarini, Alberto; Budriesi, Roberta; Bruni, Giancarlo; Romeo, Maria R. c | - | |
| Novel Ligands Specific for Mitochondrial Benzodiazepine Receptors: 6-arylpyrrolo[2,1-d][1,5]benzothiazepine Derivatives. Synthesis, Structure-Activity Relationships, and Molecular Modeling Studies | 1-gen-1994 | Fiorini, Isabella; Nacci, Vito; Ciani, Silvia Maria; Garofalo, Antonio; Campiani, Giuseppe; Savini, Luisa; Novellino, Ettore; Greco, Gianni; Bernasconi, Paola; Mennini, Tiziana | - | |
| Synthesis and “in vitro” cardiovascular activity of 4-aryl-2,3,3a,4-tetrahydro-1h-pyrrolo[2,1-c][1,4]benzothiazin-1-ones and 7-acetoxy-6-phenyl-7a,8,9,10-tetrahydropyrrolo [2,1,-d][1,5]benzothiazepin-10-one | 1-gen-1994 | Campiani, G.; Garofalo, A.; Fiorini, I.; Nacci, V.; Botta, M.; Tafi, A.; Chiarini, A.; Budriesi, R.; Bruni, G.; Romeo, M. R. | - | |
| A Comparative Molecular Field Analysis Model for 6-Arylpyrrolo[2,1-d][1,5]benzothiazepines Binding Selectively to the Mitochondrial Benzodiazepine Receptor | 1-gen-1994 | Greco, Giovanni; Novellino, Ettore; Fiorini, Isabella; Nacci, Vito; Campiani, Giuseppe; Ciani, Silvia M.; Garofalo, Antonio; Bernasconi, Paola; Mennini, Tiziana | - | |
| Benzothiazine and Benzothiazepine derivatives: synthesis and preliminary biological evaluation | 1-gen-1993 | Garofalo, A.; Campiani, G.; Fiorini, I.; Nacci, V. | - | |
| Pyrazolo[4,3-c]quinolines. Synthesis and specific inhibition of benzodiazepine receptor binding (Note I) | 1-gen-1993 | Savini, Luisa; Massarelli, Paola; Pellerano, Cesare; Fiorini, Isabella; Bruni, Giancarlo; Romeo, M. R. | - | |
| Synthesis and preliminary biological evaluation of 1-aminomethyl-4-substituted-4-H-pyrrolo[2,1-C][1,4] benzothiazines, a new class of calcium antagonists | 1-gen-1992 | Campiani, G.; Nacci, V.; Garofalo, A.; Botta, M.; Fiorini, I.; Tafi, A.; Bruni, G.; Romeo, M. R.; Peres, A.; Bertollini, L. | - | |
| Polycondensed heterocycles. VIII. Synthesis of 11-aryl-5H,11H-Pyrrolo[2,1-c][1,4]benzothiazepines by Pummerer rearrangement-cyclization reaction | 1-gen-1992 | Garofalo, Antonio; Campiani, Giuseppe; Nacci, Vito; Fiorini, Isabella | - |
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