Sfoglia per Autore
Reversing TGF-β1-induced fibrotic phenotype in human lung fibroblasts using a PROTAC tool derived from an indoline-based HDAC6 inhibitor
2025-01-01 Cursaro, Ilaria; Ciccone, Valerio; Tudino, Valeria; Papulino, Chiara; Scalvini, Laura; Donnini, Sandra; Morbidelli, Lucia; Bini, Luca; Landi, Claudia; Contri, Chiara; Pasquini, Silvia; Vincenzi, Fabrizio; Varani, Katia; Lodola, Alessio; Mor, Marco; Benedetti, Rosaria; Altucci, Lucia; Butini, Stefania; Carullo, Gabriele; Gemma, Sandra; Campiani, Giuseppe
Uncovering a Mutation-Independent Therapeutic Strategy against Inherited Retinal Diseases: Development of Class I HDAC/LSD1 Hybrid Inhibitors
2025-01-01 Carullo, Gabriele; Piano, Ilaria; Salamone, Giulia; Corsi, Francesca; Orsini, Noemi; Dichiara, Maria; Cursaro, Ilaria; Fontana, Anna; Galante, Alessia; Contri, Chiara; Guadagno, Ludovica; Caroli, Jonatan; Mattevi, Andrea; Vincenzi, Fabrizio; Varani, Katia; Brogi, Simone; Gemma, Sandra; Butini, Stefania; Gargini, Claudia; Strettoi, Enrica; Campiani, Giuseppe
Targeting N‐Methyl‐lysine Histone Demethylase KDM4 in Cancer: Natural Products Inhibitors as a Driving Force for Epigenetic Drug Discovery
2025-01-01 Cursaro, Ilaria; Milioni, Leonardo; Eslami, Kourosh; Sirous, Hajar; Carullo, Gabriele; Gemma, Sandra; Butini, Stefania; Campiani, Giuseppe
Unveiling Wound Healing Properties of Biostimulated Walnut Kernel Extracts via Epithelial Mesenchymal Transition: Switching a Nutritional Matrix into a Therapeutic Remedy
2025-01-01 Fedeli, Riccardo; Ranzato, Elia; Martinotti, Simona; Basilicata, Manuela Giovanna; Marotta, Ludovica; Fava, Marianna; Cursaro, Ilaria; Tremori, Giulio; Bonsignore, Gregorio; Carullo, Gabriele; Gemma, Sandra; Aquino, Giovanna; Campiglia, Pietro; Pepe, Giacomo; Butini, Stefania; Loppi, Stefano; Campiani, Giuseppe
Spirotetrahydroisoquinoline-Based Histone Deacetylase Inhibitors as New Antifibrotic Agents: Biological Evaluation in Human Fibroblasts from Bronchoalveolar Lavages of Idiopathic Pulmonary Fibrosis Patients
2025-01-01 Fontana, Anna; Bergantini, Laura; Carullo, Gabriele; Scalvini, Laura; D'Alessandro, Miriana; Papulino, Chiara; Cameli, Paolo; Gangi, Sara; Vincenzi, Fabrizio; Varani, Katia; Contri, Chiara; Pasquini, Silvia; Pistocchi, Anna; Pezzotta, Alex; Carbone, Sabrina; Saponara, Simona; Gemma, Sandra; Altucci, Lucia; Benedetti, Rosaria; Lodola, Alessio; Mor, Marco; Bargagli, Elena; Butini, Stefania; Campiani, Giuseppe
The insulin-releasing agent quercetin-3-oleate stimulates CaV1.2 channels similarly to quercetin, though with a reduced vasorelaxant activity
2025-01-01 Fusi, Fabio; Saponara, Simona; Carullo, Gabriele; Panti, Alice; Bichicchi, Alessia; Pifferi, Alice; Gianibbi, Beatrice; Spiga, Ottavia; Falbo, Federica; Spizzirri, Umile Gianfranco; Campiani, Giuseppe; Aiello, Francesca
Discovery of p-Trifluoromethylbenzohydrazide Derivatives as Potent Antiviral Agents against Monkeypox Virus
2025-01-01 Rossi, Sara; Pozzetti, Luca; Carullo, Gabriele; Dichiara, Maria; Butini, Stefania; Radi, Marco; Ramunno, Anna; Terrosi, Chiara; Barra, Giovanni; Berisio, Rita; Gemma, Sandra; Cusi, Maria Grazia; Campiani, Giuseppe
Synthesis and biological investigation of peptidomimetic SARS‐CoV‐2 main protease inhibitors bearing quinoline‐based heterocycles at P3
2025-01-01 Rossi, Sara; Deidda, Graziano; Fiaschi, Lia; Ibba, Roberta; Pieroni, Mariachiara; Dichiara, Maria; Carullo, Gabriele; Butini, Stefania; Ramunno, Anna; Brogi, Simone; Lolicato, Marco; Arrigoni, Cristina; Cabella, Noemi; Bavagnoli, Laura; Maga, Giovanni; Varasi, Ilenia; Biba, Camilla; Vicenti, Ilaria; Gemma, Sandra; Crespan, Emmanuele; Zazzi, Maurizio; Campiani, Giuseppe
Agri-food traceability today: Advancing innovation towards efficiency, sustainability, ethical sourcing, and safety in food supply chains
2025-01-01 Rossi, Sara; Gemma, Sandra; Borghini, Francesca; Perini, Matteo; Butini, Stefania; Carullo, Gabriele; Campiani, Giuseppe
Unlocking the potential of biostimulants in sustainable agriculture: Effect of wood distillate on the nutritional profiling of apples
2024-01-01 Fedeli, Riccardo; Dichiara, Maria; Carullo, Gabriele; Tudino, Valeria; Gemma, Sandra; Butini, Stefania; Campiani, Giuseppe; Loppi, Stefano
Development of Epigenetic Modifiers with Therapeutic Potential in FMS-Related Tyrosine Kinase 3/Internal Tandem Duplication (FLT3/ITD) Acute Myeloid Leukemia and Other Blood Malignancies
2024-01-01 Carullo, Gabriele; Rossi, Sara; Giudice, Valentina; Pezzotta, Alex; Chianese, Ugo; Scala, Pasqualina; Carbone, Sabrina; Fontana, Anna; Panzeca, Giovanna; Pasquini, Silvia; Contri, Chiara; Gemma, Sandra; Ramunno, Anna; Saponara, Simona; Galvani, Francesca; Lodola, Alessio; Mor, Marco; Benedetti, Rosaria; Selleri, Carmine; Varani, Katia; Butini, Stefania; Altucci, Lucia; Vincenzi, Fabrizio; Pistocchi, Anna; Campiani, Giuseppe
Effects of structurally distinct human HDAC6 and HDAC6/HDAC8 inhibitors against S. mansoni larval and adult worm stages
2024-01-01 Gimmelli, Roberto; Papoff, Giuliana; Saccoccia, Fulvio; Lalli, Cristiana; Gemma, Sandra; Campiani, Giuseppe; Ruberti, Giovina
Metalloenzyme Inhibitors against Zoonotic Infections: Focus on Leishmania and Schistosoma
2024-01-01 Rossi, Sara; Tudino, Valeria; Carullo, Gabriele; Butini, Stefania; Campiani, Giuseppe; Gemma, Sandra
Exploring the chemical space around chrysin to develop novel vascular CaV1.2 channel blockers, promising vasorelaxant agents
2024-01-01 Falbo, Federica; Carullo, Gabriele; Panti, Alice; Spiga, Ottavia; Gianibbi, Beatrice; Ahmed, Amer; Campiani, Giuseppe; Ramunno, Anna; Aiello, Francesca; Fusi, Fabio
Biostimulants for Sustainable Food Production: Effects of Wood Distillate to Fortify Chickpea Flour for Development of Functional Bakery Products
2024-01-01 Fedeli, Riccardo; Spizzirri, Umile Gianfranco; Aquino, Giovanna; Basilicata, Manuela Giovanna; Pepe, Giacomo; Campiglia, Pietro; Celletti, Silvia; Tudino, Valeria; Dichiara, Maria; Gemma, Sandra; Butini, Stefania; Carullo, Gabriele; Aiello, Francesca; Restuccia, Donatella; Campiani, Giuseppe; Loppi, Stefano
Traceability and authentication in agri-food production: A multivariate approach to the characterization of the Italian food excellence elephant garlic (Allium ampeloprasum L.), a vasoactive nutraceutical
2024-01-01 Carullo, G.; Borghini, F.; Fusi, F.; Saponara, S.; Fontana, A.; Pozzetti, L.; Fedeli, R.; Panti, A.; Gorelli, B.; Aquino, G.; Basilicata, M. G.; Pepe, G.; Campiglia, P.; Biagiotti, S.; Gemma, S.; Butini, S.; Pianezze, S.; Loppi, S.; Cavaglioni, A.; Perini, M.; Campiani, G.
Synthetic derivatives of natural cinnamic acids as potential anti-colorectal cancer agents
2024-01-01 Falbo, F.; Gemma, S.; Koch, A.; Mazzotta, S.; Carullo, G.; Ramunno, A.; Butini, S.; Schneider-Stock, R.; Campiani, G.; Aiello, F.
Targeting Relevant HDACs to Support the Survival of Cone Photoreceptors in Inherited Retinal Diseases: Identification of a Potent Pharmacological Tool with In Vitro and In Vivo Efficacy
2024-01-01 Carullo, Gabriele; Orsini, Noemi; Piano, Ilaria; Pozzetti, Luca; Papa, Alessandro; Fontana, Anna; Napoli, Debora; Corsi, Francesca; Marco, Beatrice Di; Galante, Alessia; Marotta, Ludovica; Panzeca, Giovanna; O'Brien, Justine; Sanchez, Alicia Gomez; Doherty, Harry; Mahon, Niamh; Clarke, Leni; Contri, Chiara; Pasquini, Silvia; Gorelli, Beatrice; Saponara, Simona; Valoti, Massimo; Vincenzi, Fabrizio; Varani, Katia; Ramunno, Anna; Brogi, Simone; Butini, Stefania; Gemma, Sandra; Kennedy, Breandán N.; Gargini, Claudia; Strettoi, Enrica; Campiani, Giuseppe
Development of Potent and Selective Monoacylglycerol Lipase Inhibitors. SARs, Structural Analysis, and Biological Characterization
2024-01-01 Butini, Stefania; Grether, Uwe; Jung, Kwang-Mook; Ligresti, Alessia; Allarà, Marco; Postmus, Annemarieke G. J.; Maramai, Samuele; Brogi, Simone; Papa, Alessandro; Carullo, Gabriele; Sykes, David; Veprintsev, Dmitry; Federico, Stefano; Grillo, Alessandro; Di Guglielmo, Bruno; Ramunno, Anna; Stevens, Anna Floor; Heer, Dominik; Lamponi, Stefania; Gemma, Sandra; Benz, Jörg; Di Marzo, Vincenzo; van der Stelt, Mario; Piomelli, Daniele; Campiani, Giuseppe
Enhancing Drug Discovery and Development through the Integration of Medicinal Chemistry, Chemical Biology, and Academia-Industry Partnerships: Insights from Roche’s Endocannabinoid System Projects
2024-01-01 Aebi, Johannes; Atz, Kenneth; Ametamey, Simon M.; Benz, Jörg; Blaising, Julie; Butini, Stefania; Campiani, Giuseppe; Carreira, Erick M.; Collin, Ludovic; De Lago, Eva; Gazzi, Thais; Gertsch, Jürg; Gobbi, Luca; Guba, Wolfgang; Fernández-Ruiz, Javier; Fingerle, Jürgen; Haider, Ahmed; He, Yingfang; Heitman, Laura H.; Honer, Michael; Hunziker, Daniel; Kuhn, Bernd; Maccarrone, Mauro; Märki, Hans Peter; Martin, Rainer E.; Mohr, Peter; Mu, Linjing; Nazaré, Marc; Nippa, David F.; Oddi, Sergio; O'Hara, Fionn; Pacher, Pal; Romero, Julian; Röver, Stephan; Rufer, Arne C.; Schibli, Roger; Schneider, Gisbert; Stepan, Antonia F.; Sykes, David A.; Ullmer, Christoph; Van Der Stelt, Mario; Veprintsev, Dmitry B.; Wittwer, Matthias B.; Grether, Uwe
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| Reversing TGF-β1-induced fibrotic phenotype in human lung fibroblasts using a PROTAC tool derived from an indoline-based HDAC6 inhibitor | 1-gen-2025 | Cursaro, Ilaria; Ciccone, Valerio; Tudino, Valeria; Papulino, Chiara; Scalvini, Laura; Donnini, Sandra; Morbidelli, Lucia; Bini, Luca; Landi, Claudia; Contri, Chiara; Pasquini, Silvia; Vincenzi, Fabrizio; Varani, Katia; Lodola, Alessio; Mor, Marco; Benedetti, Rosaria; Altucci, Lucia; Butini, Stefania; Carullo, Gabriele; Gemma, Sandra; Campiani, Giuseppe | - | |
| Uncovering a Mutation-Independent Therapeutic Strategy against Inherited Retinal Diseases: Development of Class I HDAC/LSD1 Hybrid Inhibitors | 1-gen-2025 | Carullo, Gabriele; Piano, Ilaria; Salamone, Giulia; Corsi, Francesca; Orsini, Noemi; Dichiara, Maria; Cursaro, Ilaria; Fontana, Anna; Galante, Alessia; Contri, Chiara; Guadagno, Ludovica; Caroli, Jonatan; Mattevi, Andrea; Vincenzi, Fabrizio; Varani, Katia; Brogi, Simone; Gemma, Sandra; Butini, Stefania; Gargini, Claudia; Strettoi, Enrica; Campiani, Giuseppe | - | |
| Targeting N‐Methyl‐lysine Histone Demethylase KDM4 in Cancer: Natural Products Inhibitors as a Driving Force for Epigenetic Drug Discovery | 1-gen-2025 | Cursaro, Ilaria; Milioni, Leonardo; Eslami, Kourosh; Sirous, Hajar; Carullo, Gabriele; Gemma, Sandra; Butini, Stefania; Campiani, Giuseppe | - | |
| Unveiling Wound Healing Properties of Biostimulated Walnut Kernel Extracts via Epithelial Mesenchymal Transition: Switching a Nutritional Matrix into a Therapeutic Remedy | 1-gen-2025 | Fedeli, Riccardo; Ranzato, Elia; Martinotti, Simona; Basilicata, Manuela Giovanna; Marotta, Ludovica; Fava, Marianna; Cursaro, Ilaria; Tremori, Giulio; Bonsignore, Gregorio; Carullo, Gabriele; Gemma, Sandra; Aquino, Giovanna; Campiglia, Pietro; Pepe, Giacomo; Butini, Stefania; Loppi, Stefano; Campiani, Giuseppe | - | |
| Spirotetrahydroisoquinoline-Based Histone Deacetylase Inhibitors as New Antifibrotic Agents: Biological Evaluation in Human Fibroblasts from Bronchoalveolar Lavages of Idiopathic Pulmonary Fibrosis Patients | 1-gen-2025 | Fontana, Anna; Bergantini, Laura; Carullo, Gabriele; Scalvini, Laura; D'Alessandro, Miriana; Papulino, Chiara; Cameli, Paolo; Gangi, Sara; Vincenzi, Fabrizio; Varani, Katia; Contri, Chiara; Pasquini, Silvia; Pistocchi, Anna; Pezzotta, Alex; Carbone, Sabrina; Saponara, Simona; Gemma, Sandra; Altucci, Lucia; Benedetti, Rosaria; Lodola, Alessio; Mor, Marco; Bargagli, Elena; Butini, Stefania; Campiani, Giuseppe | - | |
| The insulin-releasing agent quercetin-3-oleate stimulates CaV1.2 channels similarly to quercetin, though with a reduced vasorelaxant activity | 1-gen-2025 | Fusi, Fabio; Saponara, Simona; Carullo, Gabriele; Panti, Alice; Bichicchi, Alessia; Pifferi, Alice; Gianibbi, Beatrice; Spiga, Ottavia; Falbo, Federica; Spizzirri, Umile Gianfranco; Campiani, Giuseppe; Aiello, Francesca | - | |
| Discovery of p-Trifluoromethylbenzohydrazide Derivatives as Potent Antiviral Agents against Monkeypox Virus | 1-gen-2025 | Rossi, Sara; Pozzetti, Luca; Carullo, Gabriele; Dichiara, Maria; Butini, Stefania; Radi, Marco; Ramunno, Anna; Terrosi, Chiara; Barra, Giovanni; Berisio, Rita; Gemma, Sandra; Cusi, Maria Grazia; Campiani, Giuseppe | - | |
| Synthesis and biological investigation of peptidomimetic SARS‐CoV‐2 main protease inhibitors bearing quinoline‐based heterocycles at P3 | 1-gen-2025 | Rossi, Sara; Deidda, Graziano; Fiaschi, Lia; Ibba, Roberta; Pieroni, Mariachiara; Dichiara, Maria; Carullo, Gabriele; Butini, Stefania; Ramunno, Anna; Brogi, Simone; Lolicato, Marco; Arrigoni, Cristina; Cabella, Noemi; Bavagnoli, Laura; Maga, Giovanni; Varasi, Ilenia; Biba, Camilla; Vicenti, Ilaria; Gemma, Sandra; Crespan, Emmanuele; Zazzi, Maurizio; Campiani, Giuseppe | - | |
| Agri-food traceability today: Advancing innovation towards efficiency, sustainability, ethical sourcing, and safety in food supply chains | 1-gen-2025 | Rossi, Sara; Gemma, Sandra; Borghini, Francesca; Perini, Matteo; Butini, Stefania; Carullo, Gabriele; Campiani, Giuseppe | - | |
| Unlocking the potential of biostimulants in sustainable agriculture: Effect of wood distillate on the nutritional profiling of apples | 1-gen-2024 | Fedeli, Riccardo; Dichiara, Maria; Carullo, Gabriele; Tudino, Valeria; Gemma, Sandra; Butini, Stefania; Campiani, Giuseppe; Loppi, Stefano | - | |
| Development of Epigenetic Modifiers with Therapeutic Potential in FMS-Related Tyrosine Kinase 3/Internal Tandem Duplication (FLT3/ITD) Acute Myeloid Leukemia and Other Blood Malignancies | 1-gen-2024 | Carullo, Gabriele; Rossi, Sara; Giudice, Valentina; Pezzotta, Alex; Chianese, Ugo; Scala, Pasqualina; Carbone, Sabrina; Fontana, Anna; Panzeca, Giovanna; Pasquini, Silvia; Contri, Chiara; Gemma, Sandra; Ramunno, Anna; Saponara, Simona; Galvani, Francesca; Lodola, Alessio; Mor, Marco; Benedetti, Rosaria; Selleri, Carmine; Varani, Katia; Butini, Stefania; Altucci, Lucia; Vincenzi, Fabrizio; Pistocchi, Anna; Campiani, Giuseppe | - | |
| Effects of structurally distinct human HDAC6 and HDAC6/HDAC8 inhibitors against S. mansoni larval and adult worm stages | 1-gen-2024 | Gimmelli, Roberto; Papoff, Giuliana; Saccoccia, Fulvio; Lalli, Cristiana; Gemma, Sandra; Campiani, Giuseppe; Ruberti, Giovina | - | |
| Metalloenzyme Inhibitors against Zoonotic Infections: Focus on Leishmania and Schistosoma | 1-gen-2024 | Rossi, Sara; Tudino, Valeria; Carullo, Gabriele; Butini, Stefania; Campiani, Giuseppe; Gemma, Sandra | - | |
| Exploring the chemical space around chrysin to develop novel vascular CaV1.2 channel blockers, promising vasorelaxant agents | 1-gen-2024 | Falbo, Federica; Carullo, Gabriele; Panti, Alice; Spiga, Ottavia; Gianibbi, Beatrice; Ahmed, Amer; Campiani, Giuseppe; Ramunno, Anna; Aiello, Francesca; Fusi, Fabio | - | |
| Biostimulants for Sustainable Food Production: Effects of Wood Distillate to Fortify Chickpea Flour for Development of Functional Bakery Products | 1-gen-2024 | Fedeli, Riccardo; Spizzirri, Umile Gianfranco; Aquino, Giovanna; Basilicata, Manuela Giovanna; Pepe, Giacomo; Campiglia, Pietro; Celletti, Silvia; Tudino, Valeria; Dichiara, Maria; Gemma, Sandra; Butini, Stefania; Carullo, Gabriele; Aiello, Francesca; Restuccia, Donatella; Campiani, Giuseppe; Loppi, Stefano | - | |
| Traceability and authentication in agri-food production: A multivariate approach to the characterization of the Italian food excellence elephant garlic (Allium ampeloprasum L.), a vasoactive nutraceutical | 1-gen-2024 | Carullo, G.; Borghini, F.; Fusi, F.; Saponara, S.; Fontana, A.; Pozzetti, L.; Fedeli, R.; Panti, A.; Gorelli, B.; Aquino, G.; Basilicata, M. G.; Pepe, G.; Campiglia, P.; Biagiotti, S.; Gemma, S.; Butini, S.; Pianezze, S.; Loppi, S.; Cavaglioni, A.; Perini, M.; Campiani, G. | - | |
| Synthetic derivatives of natural cinnamic acids as potential anti-colorectal cancer agents | 1-gen-2024 | Falbo, F.; Gemma, S.; Koch, A.; Mazzotta, S.; Carullo, G.; Ramunno, A.; Butini, S.; Schneider-Stock, R.; Campiani, G.; Aiello, F. | - | |
| Targeting Relevant HDACs to Support the Survival of Cone Photoreceptors in Inherited Retinal Diseases: Identification of a Potent Pharmacological Tool with In Vitro and In Vivo Efficacy | 1-gen-2024 | Carullo, Gabriele; Orsini, Noemi; Piano, Ilaria; Pozzetti, Luca; Papa, Alessandro; Fontana, Anna; Napoli, Debora; Corsi, Francesca; Marco, Beatrice Di; Galante, Alessia; Marotta, Ludovica; Panzeca, Giovanna; O'Brien, Justine; Sanchez, Alicia Gomez; Doherty, Harry; Mahon, Niamh; Clarke, Leni; Contri, Chiara; Pasquini, Silvia; Gorelli, Beatrice; Saponara, Simona; Valoti, Massimo; Vincenzi, Fabrizio; Varani, Katia; Ramunno, Anna; Brogi, Simone; Butini, Stefania; Gemma, Sandra; Kennedy, Breandán N.; Gargini, Claudia; Strettoi, Enrica; Campiani, Giuseppe | - | |
| Development of Potent and Selective Monoacylglycerol Lipase Inhibitors. SARs, Structural Analysis, and Biological Characterization | 1-gen-2024 | Butini, Stefania; Grether, Uwe; Jung, Kwang-Mook; Ligresti, Alessia; Allarà, Marco; Postmus, Annemarieke G. J.; Maramai, Samuele; Brogi, Simone; Papa, Alessandro; Carullo, Gabriele; Sykes, David; Veprintsev, Dmitry; Federico, Stefano; Grillo, Alessandro; Di Guglielmo, Bruno; Ramunno, Anna; Stevens, Anna Floor; Heer, Dominik; Lamponi, Stefania; Gemma, Sandra; Benz, Jörg; Di Marzo, Vincenzo; van der Stelt, Mario; Piomelli, Daniele; Campiani, Giuseppe | - | |
| Enhancing Drug Discovery and Development through the Integration of Medicinal Chemistry, Chemical Biology, and Academia-Industry Partnerships: Insights from Roche’s Endocannabinoid System Projects | 1-gen-2024 | Aebi, Johannes; Atz, Kenneth; Ametamey, Simon M.; Benz, Jörg; Blaising, Julie; Butini, Stefania; Campiani, Giuseppe; Carreira, Erick M.; Collin, Ludovic; De Lago, Eva; Gazzi, Thais; Gertsch, Jürg; Gobbi, Luca; Guba, Wolfgang; Fernández-Ruiz, Javier; Fingerle, Jürgen; Haider, Ahmed; He, Yingfang; Heitman, Laura H.; Honer, Michael; Hunziker, Daniel; Kuhn, Bernd; Maccarrone, Mauro; Märki, Hans Peter; Martin, Rainer E.; Mohr, Peter; Mu, Linjing; Nazaré, Marc; Nippa, David F.; Oddi, Sergio; O'Hara, Fionn; Pacher, Pal; Romero, Julian; Röver, Stephan; Rufer, Arne C.; Schibli, Roger; Schneider, Gisbert; Stepan, Antonia F.; Sykes, David A.; Ullmer, Christoph; Van Der Stelt, Mario; Veprintsev, Dmitry B.; Wittwer, Matthias B.; Grether, Uwe | - |
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