Riboflavin UV-A Corneal Crosslinking was developed in the 1990s to treat progressive keratoconus. Its indication was rapidly extended to iatrogenic corneal ectasias. Conventional 3mW/cm2 CXL represents the gold standard therapy in multiple Countries around the World to halt the progression of early stages corneal ectasia demonstrating good long-term visual results and low complications. Early diagnosis, slowing the progression of keratoconus turning to native corneal crosslinking spirit: stabilizing ectasia progression preventing corneal shape modification, is the key. Conventional and Accelerated CXL protocols demonstrated a medium-long term improvement in visual and topo-aberrometric parameters. New conservative approaches such as topography-guided CXL and CXL-plus corneal reshaping techniques are under investigation for patients with poor spectacles corrected visual acuity and contact lenses intolerance before keratoplasty.
Mazzotta, C.G., Rechichi, M., Traversi, C., Baiocchi, S., Polito, M.S., Caragiuli, S. (2016). Slowing the Progression of Keratoconus - Turning to Corneal Crosslinking. EXPERT REVIEW OF OPHTHALMOLOGY, 11(1), 41-48 [10.1586/17469899.2016.1136788].
Slowing the Progression of Keratoconus - Turning to Corneal Crosslinking
MAZZOTTA, COSIMO GIUSEPPE;TRAVERSI, CLAUDIO;BAIOCCHI, STEFANO;
2016-01-01
Abstract
Riboflavin UV-A Corneal Crosslinking was developed in the 1990s to treat progressive keratoconus. Its indication was rapidly extended to iatrogenic corneal ectasias. Conventional 3mW/cm2 CXL represents the gold standard therapy in multiple Countries around the World to halt the progression of early stages corneal ectasia demonstrating good long-term visual results and low complications. Early diagnosis, slowing the progression of keratoconus turning to native corneal crosslinking spirit: stabilizing ectasia progression preventing corneal shape modification, is the key. Conventional and Accelerated CXL protocols demonstrated a medium-long term improvement in visual and topo-aberrometric parameters. New conservative approaches such as topography-guided CXL and CXL-plus corneal reshaping techniques are under investigation for patients with poor spectacles corrected visual acuity and contact lenses intolerance before keratoplasty.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
https://hdl.handle.net/11365/998229