Neisseria meningitidis infection represents a major life-threatening bacterial disease worldwide. Genomics has revolutionized every aspect of the field of microbiology. As a consequence of genome sequencing, the postgenomic era commenced 15 years ago. Comparative genomics, functional genomics and proteomics, as well as a combination of these techniques, will play important roles in providing vital information regarding bacterial biological complexity and pathogenic traits, and accelerate the development of therapeutic drugs and vaccines for combating infections. This review summarizes the current knowledge regarding different approaches aimed to shed light on meningococcal biology and pathogenesis, and to accelerate the development and characterization of vaccines against pathogenic meningococci. © 2009 Expert Reviews Ltd.

Bernardini, G., Braconi, D., Lusini, P., Santucci, A. (2009). Postgenomics of Neisseria meningitidis: An update. EXPERT REVIEW OF PROTEOMICS, 6(2), 135-143 [10.1586/epr.09.3].

Postgenomics of Neisseria meningitidis: An update

BERNARDINI, GIULIA;BRACONI, DANIELA;LUSINI, PAOLA;SANTUCCI, ANNALISA
2009-01-01

Abstract

Neisseria meningitidis infection represents a major life-threatening bacterial disease worldwide. Genomics has revolutionized every aspect of the field of microbiology. As a consequence of genome sequencing, the postgenomic era commenced 15 years ago. Comparative genomics, functional genomics and proteomics, as well as a combination of these techniques, will play important roles in providing vital information regarding bacterial biological complexity and pathogenic traits, and accelerate the development of therapeutic drugs and vaccines for combating infections. This review summarizes the current knowledge regarding different approaches aimed to shed light on meningococcal biology and pathogenesis, and to accelerate the development and characterization of vaccines against pathogenic meningococci. © 2009 Expert Reviews Ltd.
Bernardini, G., Braconi, D., Lusini, P., Santucci, A. (2009). Postgenomics of Neisseria meningitidis: An update. EXPERT REVIEW OF PROTEOMICS, 6(2), 135-143 [10.1586/epr.09.3].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11365/997033
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