BACKGROUND: Gastric stump carcinoma (GSC) has been studied after primary gastrectomy for benign disease but few studies have evaluated its correlation with gastric cancer. PATIENTS: We assessed 541 patients submitted to subtotal gastrectomy for early gastric cancer at least 15 years ago. RESULTS: GSC was diagnosed in 16 (2.9%) patients, giving a 4% cumulative risk of GSC 20 years after surgery. Diagnosis was made within 5 years of surgery in 10 patients and after 8 years in 6 cases. GSC occurred in 13/470 (2.8%) patients submitted to Billroth 2 reconstruction, 2/30 (6.7%) patients who underwent Billroth 1, and 1/41 (2.4%) patients after Roux-en-Y reconstruction. Significant risk factors observed for GSC were histologic type and sex. Other synchronous or metachronous extragastric tumors were registered in 56 (11.2%) patients. CONCLUSIONS: The risk of GSC was low, even 20 years after subtotal gastrectomy for early gastric cancer. Lauren intestinal histotype and male sex were frequently associated with GSC. No correlation was observed between GSC and reconstruction technique or multifocality. Clinically speaking, GSC could be considered a subset of gastric cancer.
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|Titolo:||Gastric stump carcinoma after distal subtotal gastrectomy for early gastric cancer: Experience of 541 patients with long-term follow-up|
|Citazione:||Morgagni, P., Gardini, A., Marrelli, D., Vittimberga, G., Marchet, A., De Manzoni, G., et al. (2015). Gastric stump carcinoma after distal subtotal gastrectomy for early gastric cancer: Experience of 541 patients with long-term follow-up. THE AMERICAN JOURNAL OF SURGERY, 209(6), 1063-1068.|
|Appare nelle tipologie:||1.1 Articolo in rivista|
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