Superinfection with drug resistant HIV strains could potentially contribute to compromised therapy in patients initially infected with drug-sensitive virus and receiving antiretroviral therapy. To investigate the importance of this potential route to drug resistance, we developed a bioinformatics pipeline to detect superinfection from routinely collected genotyping data, and assessed whether superinfection contributed to increased drug resistance in a large European cohort of viremic, drug treated patients.
|Titolo:||Superinfection with drug-resistant HIV is rare and does not contribute substantially to therapy failure in a large European cohort|
|Citazione:||Superinfection with drug-resistant HIV is rare and does not contribute substantially to therapy failure in a large European cohort / Bartha, István; Assel, Matthias; Sloot, Peter M. A; Zazzi, Maurizio; Torti, Carlo; Schülter, Eugen; De Luca, Andrea; Sönnerborg, Anders; Abecasis, Ana B; Van Laethem, Kristel; Rosi, Andrea; Svärd, Jenny; Paredes, Roger; van de Vijver, David A. M. C; Vandamme, Anne Mieke; Müller, Viktor. - In: BMC INFECTIOUS DISEASES. - ISSN 1471-2334. - STAMPA. - 13:1(2013), p. 537.|
|Appare nelle tipologie:||1.1 Articolo in rivista|
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