Maraviroc is an HIV-1 coreceptor antagonist that has shown good efficacy and tolerability in treatment-naive and treatment-experienced patients harboring CCR5-tropic virus. The use of Maraviroc in treatment simplification in patients with suppressed plasma HIV-1 RNA requires analysis of HIV-1 DNA. Coreceptor tropism testing is often performed remotely at reference laboratories. In this study paired whole blood stored at + 4 °C and at-20°C were compared as a source for genotypic coreceptor tropism testing.
|Titolo:||Stability of unfrozen whole blood DNA for remote genotypic analysis of HIV-1 coreceptor tropism|
|Citazione:||Meini, G., Materazzi, A., Saladini, F., Rosi, A., Vicenti, I., Mancini, M., et al. (2013). Stability of unfrozen whole blood DNA for remote genotypic analysis of HIV-1 coreceptor tropism. BMC INFECTIOUS DISEASES, 13(1), 508.|
|Appare nelle tipologie:||1.1 Articolo in rivista|