Raltegravir intensification is associated with an increase in 2-LTR episomal HIV DNA= circles, indicating a persistent low-level replication, in some individuals in ART with suppressed HIV RNA. We aimed at monitoring residual plasma HIV RNA and cellular HIV DNA in virologically suppressed patients switching to a raltegravir-based regimen.
Bianco, C., Meini, G., Rossetti, B., Lamonica, S., Mondi, A., Belmonti, S., et al. (2014). Switch to raltegravir-based regimens and HIV DNA decrease in patients with suppressed HIV RNA. JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, 17(Suppl. 3), 19791-19791 [10.7448/IAS.17.4.19791].
Switch to raltegravir-based regimens and HIV DNA decrease in patients with suppressed HIV RNA
BIANCO, CLAUDIA;MEINI, GENNY;ROSSETTI, BARBARA;ZAZZI, MAURIZIO;De Luca, Andrea
2014-01-01
Abstract
Raltegravir intensification is associated with an increase in 2-LTR episomal HIV DNA= circles, indicating a persistent low-level replication, in some individuals in ART with suppressed HIV RNA. We aimed at monitoring residual plasma HIV RNA and cellular HIV DNA in virologically suppressed patients switching to a raltegravir-based regimen.
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