Patients with Lennox-Gastaut syndrome (persistent tonic, myoclonic and astatic seizures) have a poor prognosis. Seizures occurre daily in most individuals and persist in 60-80%. Callosotomy may reduce seizure frequency, particularly for those with astatic seizures, but complete control is rare. A preliminary report suggested that vagus nerve stimulation (VNS) might improve seizure control and quality of life, although to our knowledge no completely seizure-free outcome for patients with this syndrome has been reported following this approach. The authors report their experience about a 22-year-old white man suffering for astatic seizures and treated with VNS.

Buoni, S., Zannolli, R., Macucci, F., Pieri, S., Galluzzi, P., Mariottini, A., et al. (2004). Delayed response of seizures with vagus nerve stimulation in Lennox-Gastaut syndrome. NEUROLOGY, 63(8), 1539-1540 [10.1212/01.WNL.0000141854.58301.4C].

Delayed response of seizures with vagus nerve stimulation in Lennox-Gastaut syndrome

MARIOTTINI A.;
2004-01-01

Abstract

Patients with Lennox-Gastaut syndrome (persistent tonic, myoclonic and astatic seizures) have a poor prognosis. Seizures occurre daily in most individuals and persist in 60-80%. Callosotomy may reduce seizure frequency, particularly for those with astatic seizures, but complete control is rare. A preliminary report suggested that vagus nerve stimulation (VNS) might improve seizure control and quality of life, although to our knowledge no completely seizure-free outcome for patients with this syndrome has been reported following this approach. The authors report their experience about a 22-year-old white man suffering for astatic seizures and treated with VNS.
2004
Buoni, S., Zannolli, R., Macucci, F., Pieri, S., Galluzzi, P., Mariottini, A., et al. (2004). Delayed response of seizures with vagus nerve stimulation in Lennox-Gastaut syndrome. NEUROLOGY, 63(8), 1539-1540 [10.1212/01.WNL.0000141854.58301.4C].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11365/9381
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