To examine the appropriate treatment of oligo-terato-asthenozoospermic patients with metabolic syndrome, 45 patients were treated with metformin for 6 months. The use of metformin was associated with a statistically significant reduction in insulin resistance and sex hormone-binding globulin levels, a statistically significant increase in serum androgen levels, and a consequent improvement in semen characteristics. © 2011 by American Society for Reproductive Medicine.
Morgante, G., Tosti, C., Orvieto, R., Musacchio, M.C., Piomboni, P., DE LEO, V. (2011). Metformin improves semen characteristics of oligo-terato-asthenozoospermic men with metabolic syndrome. FERTILITY AND STERILITY, 95(6), 2150-2152 [10.1016/j.fertnstert.2010.12.009].
Metformin improves semen characteristics of oligo-terato-asthenozoospermic men with metabolic syndrome
Morgante, Giuseppe;Tosti, Claudia;Piomboni, Paola;DE LEO, Vincenzo
2011-01-01
Abstract
To examine the appropriate treatment of oligo-terato-asthenozoospermic patients with metabolic syndrome, 45 patients were treated with metformin for 6 months. The use of metformin was associated with a statistically significant reduction in insulin resistance and sex hormone-binding globulin levels, a statistically significant increase in serum androgen levels, and a consequent improvement in semen characteristics. © 2011 by American Society for Reproductive Medicine.
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https://hdl.handle.net/11365/7469
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