The authors report three siblings (two sisters and their aunt, aged 20, 22 and 36, respectively) with familial adenomatous polyposis (FAP) and papillary thyroid carcinoma. After diagnosis of FAP, a single, non palpable nodule was revealed in each patient by routine screening ultrasonography of the gland, The diagnosis of papillary carcinoma was made by fine-needle-aspiration biopsy of the nodules and confirmed by histologic examination of surgical specimens. A review of the literature reveals about 40 reports of such an association, that is considered not fortuitous. Nevertheless, in this family the association seems to be a distinctive, clinical feature of the syndrome, affecting three out of five members intensively screened for extracolonic lesions.

Civitelli, S., Tanzini, G., F., C., M., P., M. C., P., & B., C. (1996). Papillary Thyroid carcinoma in three siblings with familial adenomatous polyposis. INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 11(1), 34-37 [10.1007/BF00418853].

Papillary Thyroid carcinoma in three siblings with familial adenomatous polyposis

CIVITELLI, SERENELLA;TANZINI, GABRIELLO;
1996

Abstract

The authors report three siblings (two sisters and their aunt, aged 20, 22 and 36, respectively) with familial adenomatous polyposis (FAP) and papillary thyroid carcinoma. After diagnosis of FAP, a single, non palpable nodule was revealed in each patient by routine screening ultrasonography of the gland, The diagnosis of papillary carcinoma was made by fine-needle-aspiration biopsy of the nodules and confirmed by histologic examination of surgical specimens. A review of the literature reveals about 40 reports of such an association, that is considered not fortuitous. Nevertheless, in this family the association seems to be a distinctive, clinical feature of the syndrome, affecting three out of five members intensively screened for extracolonic lesions.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11365/7025
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