M protein gene typing was used to analyse Streptococcus pyogenes clinical isolates collected between 1983 and 1995 in an area of central Italy from patients presenting different types of infections; the same isolates were also characterized by means of DNA fingerprinting. M type 1 was the most common (50% of study strains), followed by M types 4, 12 and 6. The proportion of M type 12 decreased with time, whereas M type 1 increased, in agreement with data obtained in many different areas. Most invasive strains belonged to types M1 (30%) and M12 (30%); on the other hand, the M1 type did frequently occur also among noninvasive isolates. DNA fingerprinting showed a correlation between M types and DNA patterns. This report provides epidemiological information from a geographic area not sampled recently, and further shows the usefulness of the M genotyping technique, which offers potential advantages over conventional serological typing methods.

Mencarelli, M., Corbisiero, R., Marzocchi, B., Gistri, A., Signori, R., Rossolini, A., et al. (1998). M genotyping and DNA fingerprinting of Streptococcus pyogenes isolates from an area of central Italy. EPIDEMIOLOGY AND INFECTION, 212(1), 77-84 [10.1017/S0950268898008802].

M genotyping and DNA fingerprinting of Streptococcus pyogenes isolates from an area of central Italy

Marzocchi, Barbara;Rossolini, Aldo;Cellesi, Carla
1998-01-01

Abstract

M protein gene typing was used to analyse Streptococcus pyogenes clinical isolates collected between 1983 and 1995 in an area of central Italy from patients presenting different types of infections; the same isolates were also characterized by means of DNA fingerprinting. M type 1 was the most common (50% of study strains), followed by M types 4, 12 and 6. The proportion of M type 12 decreased with time, whereas M type 1 increased, in agreement with data obtained in many different areas. Most invasive strains belonged to types M1 (30%) and M12 (30%); on the other hand, the M1 type did frequently occur also among noninvasive isolates. DNA fingerprinting showed a correlation between M types and DNA patterns. This report provides epidemiological information from a geographic area not sampled recently, and further shows the usefulness of the M genotyping technique, which offers potential advantages over conventional serological typing methods.
1998
Mencarelli, M., Corbisiero, R., Marzocchi, B., Gistri, A., Signori, R., Rossolini, A., et al. (1998). M genotyping and DNA fingerprinting of Streptococcus pyogenes isolates from an area of central Italy. EPIDEMIOLOGY AND INFECTION, 212(1), 77-84 [10.1017/S0950268898008802].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11365/49608
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