Recent reports suggest that R&D productivity in the pharmaceutical industry can be strengthened by reducing costs both in the early phase and, mostly, in the clinical phase of drug discovery. However, a cost–benefit probabilistic analysis reveals that despite high costs, the clinical phase shows healthy productivity, whereas the early phase, particularly lead optimization, exhibits very low productivity.
Dimitri, N. (2011). An assessment of R&D productivity in the pharmaceutical industry. TRENDS IN PHARMACOLOGICAL SCIENCES, 32(12), 683-685 [10.1016/J.TIPS.2011.09.005].
An assessment of R&D productivity in the pharmaceutical industry
DIMITRI, NICOLA
2011-01-01
Abstract
Recent reports suggest that R&D productivity in the pharmaceutical industry can be strengthened by reducing costs both in the early phase and, mostly, in the clinical phase of drug discovery. However, a cost–benefit probabilistic analysis reveals that despite high costs, the clinical phase shows healthy productivity, whereas the early phase, particularly lead optimization, exhibits very low productivity.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
https://hdl.handle.net/11365/49410
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