The aim of this work is to obtain new technologically improved microencapsulated sunscreens characterised by UV-radiation stability, good substantivity, low toxicity, a better tolerability and easiness to formulation. For this purpose we prepared two different systems using semisynthetic Hyaluronic Acid (HA) benzyl ester and a synthetic polymer (patent pending). We obtained these systems using two different methodologies: emulsification/solvent evaporation and emulsification/solvent extraction. The comparison between the two formulated systems was carried out in terms of their chemical-physical and biological properties. © 2002 Elsevier Science B.V. All rights reserved.
Anselmi, C., Centini, M., Rossi, C., Ricci, M., Rastrelli, A., Andreassi, M., et al. (2002). New microencapsulated sunscreens: technology and comparative evaluation. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 242(1-2), 207-211 [10.1016/S0378-5173(02)00159-X].
New microencapsulated sunscreens: technology and comparative evaluation
Anselmi, Cecilia;Centini, Marisanna;Andreassi, Marco;Buonocore, Anna;La Rosa, Caterina
2002-01-01
Abstract
The aim of this work is to obtain new technologically improved microencapsulated sunscreens characterised by UV-radiation stability, good substantivity, low toxicity, a better tolerability and easiness to formulation. For this purpose we prepared two different systems using semisynthetic Hyaluronic Acid (HA) benzyl ester and a synthetic polymer (patent pending). We obtained these systems using two different methodologies: emulsification/solvent evaporation and emulsification/solvent extraction. The comparison between the two formulated systems was carried out in terms of their chemical-physical and biological properties. © 2002 Elsevier Science B.V. All rights reserved.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
https://hdl.handle.net/11365/47956
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