11β-hydroxysteroid dehydrogenase 1 and 2 (11β-HSD1 and 11β-HSD2) are involved in the complex mechanism of human parturition. The present study examined mRNA expression and activity of membrane 11β-HSD1 and placental 11β-HSD2 in postdate pregnancies according to response of labor induction. In comparison to postdate women who had spontaneous delivery or after induction the non-responders showed significantly low c and high 11β-HSD2 expression and activity These data suggest that disrupted expression and activity of 11β-HSDs may occur in some postdate pregnancies.
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|Titolo:||Postdate pregnancy: Changes of placental/membranes 11β-hydroxysteroid dehydrogenase mRNA and activity|
|Citazione:||Novembri, R., Voltolini, C., Torricelli, M., Severi, F.M., Marcolongo, P., Benedetti, A., et al. (2013). Postdate pregnancy: Changes of placental/membranes 11β-hydroxysteroid dehydrogenase mRNA and activity. PLACENTA, 34(11), 1102-1104.|
|Appare nelle tipologie:||1.1 Articolo in rivista|