Non-conventional ultrasonography (power spectrum analysis) in the management of retinoblastoma

The differential diagnosis among the diseases that may simulate retinoblastoma is supported by several techniques, however, none of them can give an undeniable answer. In the authors' opinion the tissue characterization by power spectrum analysis of the radiofrequency ultrasound data may play an important role in the backscattered signal spectrum while being sensitive to the spectral shift trend. In order to evaluate the patterns of regression and quiescence of retinoblastoma foci after conservative treatment the authors try to create a model of tissue characterization that provides information not available in conventional A and B scan ultrasonography about cell type, vascularization and necrosis.