OBJECTIVE: The aim of this study was to test the value of F(2)-isoprostane (F(2)-IsoP) levels in the pericoronal gingiva as a potential predictor of oral disability after mandibular third molar (M3M) surgery. STUDY DESIGN: Thirteen patients (5 male, 8 female) with partially impacted M3M were enrolled. Pericoronal soft tissues histology was obtained, gingival F(2)-IsoPs were measured by gas chromatography/negative-ion chemical ionization tandem mass spectrometry, and health-related quality of life (HRQOL) scores were assessed. RESULTS: A variable degree of pericoronitis was evident before the M3M surgery, with a mean level of pericoronal F(2)-IsoPs of 634.8 ± 193.5 pg/mg of tissue. A significant positive correlation between pericoronal F(2)-IsoPs and HRQOL was observed in male (r(s) = 0.440; P = .0011), but not female (r(s) = -0.062; P = .5124) patients. CONCLUSIONS: Levels of F(2)-IsoPs in the pericoronal soft tissues are correlated with the degree of oral disability after M3Ms surgery in male, but not female, patients.

Parrini, S., Chisci, G., Leoncini, S., Signorini, C., Volpi, N., Capuano, A., et al. (2012). F(2)-Isoprostanes in soft oral tissues and degree of oral disability after mandibular third molar surgery. ORAL SURGERY, ORAL MEDICINE, ORAL PATHOLOGY AND ORAL RADIOLOGY, 114(3), 344-349 [10.1016/j.oooo.2012.03.010].

F(2)-Isoprostanes in soft oral tissues and degree of oral disability after mandibular third molar surgery

Parrini, S.;Leoncini, S.;Signorini, C.;Volpi, N.;Capuano, A.;Ciccoli, L.;
2012-01-01

Abstract

OBJECTIVE: The aim of this study was to test the value of F(2)-isoprostane (F(2)-IsoP) levels in the pericoronal gingiva as a potential predictor of oral disability after mandibular third molar (M3M) surgery. STUDY DESIGN: Thirteen patients (5 male, 8 female) with partially impacted M3M were enrolled. Pericoronal soft tissues histology was obtained, gingival F(2)-IsoPs were measured by gas chromatography/negative-ion chemical ionization tandem mass spectrometry, and health-related quality of life (HRQOL) scores were assessed. RESULTS: A variable degree of pericoronitis was evident before the M3M surgery, with a mean level of pericoronal F(2)-IsoPs of 634.8 ± 193.5 pg/mg of tissue. A significant positive correlation between pericoronal F(2)-IsoPs and HRQOL was observed in male (r(s) = 0.440; P = .0011), but not female (r(s) = -0.062; P = .5124) patients. CONCLUSIONS: Levels of F(2)-IsoPs in the pericoronal soft tissues are correlated with the degree of oral disability after M3Ms surgery in male, but not female, patients.
Parrini, S., Chisci, G., Leoncini, S., Signorini, C., Volpi, N., Capuano, A., et al. (2012). F(2)-Isoprostanes in soft oral tissues and degree of oral disability after mandibular third molar surgery. ORAL SURGERY, ORAL MEDICINE, ORAL PATHOLOGY AND ORAL RADIOLOGY, 114(3), 344-349 [10.1016/j.oooo.2012.03.010].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11365/44992
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