Flurbiprofen in rheumatoid arthritis: A long-term experience

The present experience confirms the effectiveness of flurbiprofen in the treatment of rheumatoid arthritis. Significant improvements occurred within the first two months of treatment with a stabilization during the following period. No parameter worsened at the long-term observation and a very low rate of subjects (2/20, 10%) complained of slight and transitory gastrointestinal troubles. Referring to the twofold question proposed undertaking this trial, the results exclude a loss of efficacy of flurbiprofen after the first months of treatment and support of the good safety of this drug also in the long-term period.