Platelet adhesion, aggregation, secretion, and survival have been shown to be changed in atherosclerosis disease and thromboembolic phenomena thus further increasing interest on antiaggregant drugs. In this paper we present evidence that 8-chlorocarbochromen and carbochromen are significantly effective in preventing the discharge of platelet specific proteins from platelets subjects to a very weak stimulus while acetylsalicylic acid and aminophylline are ineffective in this regard.
Weber, G., Bianciardi, G., Toti, P., Massari, P., Orlando, P. (1985). Observation on the effects of some antiaggregating drugs on platelet specific protein discharge after a very weak stimulus. PHARMACOLOGICAL RESEARCH COMMUNICATIONS, 17(2), 129-135 [10.1016/0031-6989(85)90059-1].
Observation on the effects of some antiaggregating drugs on platelet specific protein discharge after a very weak stimulus
Bianciardi, Giorgio;Toti, P.;
1985-01-01
Abstract
Platelet adhesion, aggregation, secretion, and survival have been shown to be changed in atherosclerosis disease and thromboembolic phenomena thus further increasing interest on antiaggregant drugs. In this paper we present evidence that 8-chlorocarbochromen and carbochromen are significantly effective in preventing the discharge of platelet specific proteins from platelets subjects to a very weak stimulus while acetylsalicylic acid and aminophylline are ineffective in this regard.
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https://hdl.handle.net/11365/43066
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