Enzyme activities of phase I and phase II of the hepatic detoxication system were investigated in two species of fish from the Ross Sea in Antarctica. The fish had extremely low phase I enzyme (BPMO and aldrin epoxidase). The reductase regenerating enzyme activities were comparable to those found in fish of temperate seas. Transferases of cytosol showed highest activity in the conjugation of l-chloro-2.4-dinitrobenzene (CDNB) and little or no conjugation of other substrates. The GSSG reductase and the glutathione transferase with peroxidase activity (CuOOH substrate) were low; the Sedependent glutathione peroxidase activity was not detectable. Interspecific differences were found for most of the enzymes tested.
Focardi, S., Fossi, M.C., Leonzio, C., DI SIMPLICIO, P. (1989). Mixed-function oxidase activity and conjugating enzymes in two species of Antarctic fish. MARINE ENVIRONMENTAL RESEARCH, 28(1-4), 31-33 [10.1016/0141-1136(89)90179-7].
Mixed-function oxidase activity and conjugating enzymes in two species of Antarctic fish
FOCARDI, S.;FOSSI, M. C.;LEONZIO, C.;
1989-01-01
Abstract
Enzyme activities of phase I and phase II of the hepatic detoxication system were investigated in two species of fish from the Ross Sea in Antarctica. The fish had extremely low phase I enzyme (BPMO and aldrin epoxidase). The reductase regenerating enzyme activities were comparable to those found in fish of temperate seas. Transferases of cytosol showed highest activity in the conjugation of l-chloro-2.4-dinitrobenzene (CDNB) and little or no conjugation of other substrates. The GSSG reductase and the glutathione transferase with peroxidase activity (CuOOH substrate) were low; the Sedependent glutathione peroxidase activity was not detectable. Interspecific differences were found for most of the enzymes tested.File | Dimensione | Formato | |
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https://hdl.handle.net/11365/41469
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