Enzyme catalysis plays a crucial role in all biochemical processes. Natural and artificial enzymes normally exhibit a high enantioselectivity toward chiral molecules as a consequence of shape-specific noncovalent attractive and repulsive intermolecular interactions. An important step toward the elucidation of enzyme mechanisms requires a comprehensive kinetic study using simplified models under conditions, such as the gas phase, where the molecule/receptor interactions are not perturbed by medium effects. In this study we report a comparative gas-phase study along these lines.
Botta, B., Subissati, D., Tafi, A., Delle Monache, G., Filippi, A., Speranza, M. (2004). Cavity Effects on the Enantioselectivity of Chiral Amido[4]resorcinarene Stereoisomers. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, 43(36), 4767-4770 [10.1002/anie.200460663].
Cavity Effects on the Enantioselectivity of Chiral Amido[4]resorcinarene Stereoisomers
Tafi, Andrea;
2004-01-01
Abstract
Enzyme catalysis plays a crucial role in all biochemical processes. Natural and artificial enzymes normally exhibit a high enantioselectivity toward chiral molecules as a consequence of shape-specific noncovalent attractive and repulsive intermolecular interactions. An important step toward the elucidation of enzyme mechanisms requires a comprehensive kinetic study using simplified models under conditions, such as the gas phase, where the molecule/receptor interactions are not perturbed by medium effects. In this study we report a comparative gas-phase study along these lines.File | Dimensione | Formato | |
---|---|---|---|
p45.pdf
non disponibili
Tipologia:
Post-print
Licenza:
NON PUBBLICO - Accesso privato/ristretto
Dimensione
146.22 kB
Formato
Adobe PDF
|
146.22 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
https://hdl.handle.net/11365/40359
Attenzione
Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo