Enzyme catalysis plays a crucial role in all biochemical processes. Natural and artificial enzymes normally exhibit a high enantioselectivity toward chiral molecules as a consequence of shape-specific noncovalent attractive and repulsive intermolecular interactions. An important step toward the elucidation of enzyme mechanisms requires a comprehensive kinetic study using simplified models under conditions, such as the gas phase, where the molecule/receptor interactions are not perturbed by medium effects. In this study we report a comparative gas-phase study along these lines.

Botta, B., Subissati, D., Tafi, A., Delle Monache, G., Filippi, A., Speranza, M. (2004). Cavity Effects on the Enantioselectivity of Chiral Amido[4]resorcinarene Stereoisomers. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, 43(36), 4767-4770 [10.1002/anie.200460663].

Cavity Effects on the Enantioselectivity of Chiral Amido[4]resorcinarene Stereoisomers

Tafi, Andrea;
2004-01-01

Abstract

Enzyme catalysis plays a crucial role in all biochemical processes. Natural and artificial enzymes normally exhibit a high enantioselectivity toward chiral molecules as a consequence of shape-specific noncovalent attractive and repulsive intermolecular interactions. An important step toward the elucidation of enzyme mechanisms requires a comprehensive kinetic study using simplified models under conditions, such as the gas phase, where the molecule/receptor interactions are not perturbed by medium effects. In this study we report a comparative gas-phase study along these lines.
2004
Botta, B., Subissati, D., Tafi, A., Delle Monache, G., Filippi, A., Speranza, M. (2004). Cavity Effects on the Enantioselectivity of Chiral Amido[4]resorcinarene Stereoisomers. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, 43(36), 4767-4770 [10.1002/anie.200460663].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11365/40359
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