Abstract Recently, mycophenolate mofetil (MMF) has been introduced in the immunosuppressive strategy after kidney transplantation. Recently, the existence of a MMF associated embriopathy has been hypothesized, namely, multiple craniofacial malformations. Only 1 report has described chorioretinal coloboma. We report a case of woman who used MMF throughout pregnancy after kidney transplantation. Her newborn developed coloboma of the right eye associated with an ocular cyst without any other malformation. The other drugs used by our patient are not considered teratogenic. Therefore, it seems reasonable to conclude a causal relationship between MMF and the malformation observed in this newborn.

DEI MALATESTA, M.f., Rocca, B., Gentile, T., Hadjistilianou, T., Borri, M., DE FRANCESCO, S., et al. (2009). A case of coloboma in a newborn to a woman taking mycophenolate mofetil in pregnancy after kidney transplantation. TRANSPLANTATION PROCEEDINGS, 41(4), 1407-1409 [10.1016/j.transproceed.2009.03.088].

A case of coloboma in a newborn to a woman taking mycophenolate mofetil in pregnancy after kidney transplantation.

HADJISTILIANOU, THEODORA;DE FRANCESCO, SONIA;
2009-01-01

Abstract

Abstract Recently, mycophenolate mofetil (MMF) has been introduced in the immunosuppressive strategy after kidney transplantation. Recently, the existence of a MMF associated embriopathy has been hypothesized, namely, multiple craniofacial malformations. Only 1 report has described chorioretinal coloboma. We report a case of woman who used MMF throughout pregnancy after kidney transplantation. Her newborn developed coloboma of the right eye associated with an ocular cyst without any other malformation. The other drugs used by our patient are not considered teratogenic. Therefore, it seems reasonable to conclude a causal relationship between MMF and the malformation observed in this newborn.
2009
DEI MALATESTA, M.f., Rocca, B., Gentile, T., Hadjistilianou, T., Borri, M., DE FRANCESCO, S., et al. (2009). A case of coloboma in a newborn to a woman taking mycophenolate mofetil in pregnancy after kidney transplantation. TRANSPLANTATION PROCEEDINGS, 41(4), 1407-1409 [10.1016/j.transproceed.2009.03.088].
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11365/401671
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo