A healthy 27-year-old woman presented, four months after childbirth, ingravescent pain and claudication of the left lower limb. Magnetic Resonance Imaging of the lumbosacral and iliac regions showed widespread muscular-skeletal lesions. The patient underwent surgery; Cryptococcus neoformans was isolated from surgical samples. Liposomal amphotericin B, fluconazole and itraconazole were administered. Laboratory findings showed lymphocytopenia, with reduction of CD4+ lymphocytes (23 cells per cubic millimeter) in the absence of HIV infection and any other defined immunodeficiency. This is a rare case of muscular-skeletal cryptococcal infection isolated in a subject affected with idiopathic CD4+ lymphocytopenia.

Zanelli, G., Sansoni, A., Ricciardi, B., Ciacci, C., & Cellesi, C. (2001). Muscular-skeletal cryptococcosis in a patient with idiopathic CD4+ lymphopenia. MYCOPATHOLOGIA, 149, 137-139.

Muscular-skeletal cryptococcosis in a patient with idiopathic CD4+ lymphopenia.

ZANELLI, GIACOMO;CELLESI, CARLA
2001

Abstract

A healthy 27-year-old woman presented, four months after childbirth, ingravescent pain and claudication of the left lower limb. Magnetic Resonance Imaging of the lumbosacral and iliac regions showed widespread muscular-skeletal lesions. The patient underwent surgery; Cryptococcus neoformans was isolated from surgical samples. Liposomal amphotericin B, fluconazole and itraconazole were administered. Laboratory findings showed lymphocytopenia, with reduction of CD4+ lymphocytes (23 cells per cubic millimeter) in the absence of HIV infection and any other defined immunodeficiency. This is a rare case of muscular-skeletal cryptococcal infection isolated in a subject affected with idiopathic CD4+ lymphocytopenia.
Zanelli, G., Sansoni, A., Ricciardi, B., Ciacci, C., & Cellesi, C. (2001). Muscular-skeletal cryptococcosis in a patient with idiopathic CD4+ lymphopenia. MYCOPATHOLOGIA, 149, 137-139.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11365/3972
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