The aims of our study have been: to verify the long-term protection (4 or 5 years) in an at risk adult population, to whom DNA-recombinant vaccine was supplied, as well as possible conditions which can give rise to an absent or weak response to immunization. The anti-HBs determination was carried out by means of the IMX AUSAB kit. All subjects responded to vaccination. Our results confirm the DNA-recombinant vaccine’s safety and immunogenicity, and show the adults at risk with an initial titre < 600 mIU/ml, as potential candidates to a booster dose. Male sex and advanced age are conditions which influence a low response.
Gasparini, R., Pozzi, T., Montomoli, E., Fragapane, E., Civai, R., Mara, E. (1998). Vaccination against Hepatitis B - Lenght of protection among populations at risk. JOURNAL OF PREVENTIVE MEDICINE AND HYGIENE, 39, 37-41.
Vaccination against Hepatitis B - Lenght of protection among populations at risk
POZZI, TERESA;MONTOMOLI, EMANUELE;
1998-01-01
Abstract
The aims of our study have been: to verify the long-term protection (4 or 5 years) in an at risk adult population, to whom DNA-recombinant vaccine was supplied, as well as possible conditions which can give rise to an absent or weak response to immunization. The anti-HBs determination was carried out by means of the IMX AUSAB kit. All subjects responded to vaccination. Our results confirm the DNA-recombinant vaccine’s safety and immunogenicity, and show the adults at risk with an initial titre < 600 mIU/ml, as potential candidates to a booster dose. Male sex and advanced age are conditions which influence a low response.
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https://hdl.handle.net/11365/38957
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