We previously described a significant sequence homology between HIV-1 gp120 and the functional sites responsible for the specific binding of snake curare-mimetic neurotoxins and rabies virus glycoprotein to the nicotinic acetylcholine receptor. Here we report findings about the existence of a mechanism of functional molecular mimicry which could enable the binding of HIV-1 gp120 to nicotinic acetylcholine receptors in muscle cells and neurons.

Bracci, L., Lozzi, L., M., R., P., N. (1992). Binding of HIV-1 gp120 to the nicotinic receptor. FEBS LETTERS, 311(2), 115-118.

Binding of HIV-1 gp120 to the nicotinic receptor

BRACCI, LUISA;LOZZI, LUISA;
1992-01-01

Abstract

We previously described a significant sequence homology between HIV-1 gp120 and the functional sites responsible for the specific binding of snake curare-mimetic neurotoxins and rabies virus glycoprotein to the nicotinic acetylcholine receptor. Here we report findings about the existence of a mechanism of functional molecular mimicry which could enable the binding of HIV-1 gp120 to nicotinic acetylcholine receptors in muscle cells and neurons.
Bracci, L., Lozzi, L., M., R., P., N. (1992). Binding of HIV-1 gp120 to the nicotinic receptor. FEBS LETTERS, 311(2), 115-118.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11365/3845
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