PURPOSE: To compare the quality of vision with aspheric and spherical intraocular lenses (IOLs) in pseudophakic patients. METHODS: This prospective, comparative, randomized study included 250 eyes of 125 patients with bilateral cataracts. Patients were randomly assigned to receive either IOLs with a spherical biconvex optic (Acrysof SN60AT [Alcon] or Sensar AR40e [Advanced Medical Optics, AMO]) or IOLs with an aspheric optic (Acrysof IQ SN60WF [Alcon], Tecnis Z9000 [AMO], or Sofpott L161A0 [Bausch & Lomb]). Ophthalmologic examination including best spectacle-corrected visual acuity, pupil size, ocular dominance investigation, contrast sensitivity under mesopic and photopic conditions, and wavefront analysis was performed 2 months postoperatively. RESULTS: Aspheric IOLs showed better contrast sensitivity compared to spherical IOLs at spatial frequencies of 6, 12, and 18 cycles per degree (cpd) under photopic conditions and at all spatial frequencies under mesopic conditions. There was no significant difference among the three aspheric IOLs at all spatial frequencies under either photopic or mesopic conditions. Mean total spherical aberration was statistically lower in dominant eyes with aspheric IOLs (0.05±0.06, 0.11±0.1, and 0.19±0.08 μm for the Tecnis Z9000, Acrysof IQ SN60WF, and Sofport L161AO, respectively) compared with eyes with spherical IOLs (0.62±0.24 and 0.46±0.19 μm for the Acrysof SN60AT and Sensar AR40e, respectively) for a 5-mm pupil diameter. CONCLUSIONS: The aspheric IOLs had less wavefront aberrations and performed better under both photopic and mesopic contrast sensitivity compared to the spherical IOLs. These findings confirm it is possible to improve the optical performance of IOLs by modifying the surfaces.

Caporossi, A., Martone, G., Casprini, F., Rapisarda, L. (2007). Prospective randomized study of clinical performance of 3 aspheric and 2 spherical intraocular lenses in 250 eyes. JOURNAL OF REFRACTIVE SURGERY, 23(7), 639-648 [10.3928/1081-597x-20070901-02].

Prospective randomized study of clinical performance of 3 aspheric and 2 spherical intraocular lenses in 250 eyes

Caporossi A.;Martone G.;
2007-01-01

Abstract

PURPOSE: To compare the quality of vision with aspheric and spherical intraocular lenses (IOLs) in pseudophakic patients. METHODS: This prospective, comparative, randomized study included 250 eyes of 125 patients with bilateral cataracts. Patients were randomly assigned to receive either IOLs with a spherical biconvex optic (Acrysof SN60AT [Alcon] or Sensar AR40e [Advanced Medical Optics, AMO]) or IOLs with an aspheric optic (Acrysof IQ SN60WF [Alcon], Tecnis Z9000 [AMO], or Sofpott L161A0 [Bausch & Lomb]). Ophthalmologic examination including best spectacle-corrected visual acuity, pupil size, ocular dominance investigation, contrast sensitivity under mesopic and photopic conditions, and wavefront analysis was performed 2 months postoperatively. RESULTS: Aspheric IOLs showed better contrast sensitivity compared to spherical IOLs at spatial frequencies of 6, 12, and 18 cycles per degree (cpd) under photopic conditions and at all spatial frequencies under mesopic conditions. There was no significant difference among the three aspheric IOLs at all spatial frequencies under either photopic or mesopic conditions. Mean total spherical aberration was statistically lower in dominant eyes with aspheric IOLs (0.05±0.06, 0.11±0.1, and 0.19±0.08 μm for the Tecnis Z9000, Acrysof IQ SN60WF, and Sofport L161AO, respectively) compared with eyes with spherical IOLs (0.62±0.24 and 0.46±0.19 μm for the Acrysof SN60AT and Sensar AR40e, respectively) for a 5-mm pupil diameter. CONCLUSIONS: The aspheric IOLs had less wavefront aberrations and performed better under both photopic and mesopic contrast sensitivity compared to the spherical IOLs. These findings confirm it is possible to improve the optical performance of IOLs by modifying the surfaces.
2007
Caporossi, A., Martone, G., Casprini, F., Rapisarda, L. (2007). Prospective randomized study of clinical performance of 3 aspheric and 2 spherical intraocular lenses in 250 eyes. JOURNAL OF REFRACTIVE SURGERY, 23(7), 639-648 [10.3928/1081-597x-20070901-02].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11365/38446
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