Several new multifunctional molecules derived from natural sources such as amino acids and hydroxycinnamic acids were synthesized. They exhibit various activities such as emulsifying, UV-protecting, and radical scavenging, thereby conforming to the latest requirements for cosmetic ingredients. The synthesis comprises only a few steps: (i) the amino acid, the acid groups of which are protected by esterification, is coupled with ferulic or caffeic acid; (ii) the p-hydroxyl group of the cinnamic derivative reacts with dodecyl bromide in the presence of potassium carbonate (the resulting compounds are highly lipophilic and tested as water/oil (W/O) emulsifiers); (iii) these molecules, by deprotonating the acid groups of the amino acids, with successive salification, are more hydrophilic, with stronger O/W emulsifying properties. The new multifunctional surfactants might prove useful for the treatment of multiple skin conditions, including loss of cellular antioxidants, damage from free radicals, damage from UV, and others.
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|Titolo:||New multifunctional surfactants from natural phenolic acids.|
|Citazione:||Anselmi, C., Centini, M., ROSSATO MARIA, S., Sega, A., Buonocore, A., & Stefanoni, S. (2012). New multifunctional surfactants from natural phenolic acids. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 60(1), 74-80.|
|Appare nelle tipologie:||1.1 Articolo in rivista|