BACKGROUND: The poor prognosis of rheumatoid arthritis (RA) can be aggravated by the concomitant presence of chronic hepatitis C virus (HCV) infection and there are no guidelines for the treatment of patients affected by both conditions. OBJECTIVE: To propose new therapeutic strategies for patient affected by RA and concomitant HCV chronic infection. METHODS: Review of the literature on the usage of cyclosporine-A (CsA) and anti-tumour-necrosis-factor (TNF)-alpha agents for the treatment of patients affected by RA and HCV. RESULTS/CONCLUSION: CsA exerts an inhibitory effect on HCV replication and it is safe in patients affected by RA and HCV. Anti-TNF-alpha agents are safe and efficacious in patient with RA and HCV. Anti-TNF-alpha and CsA can be safely given in combination in RA patients with HCV infection.
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|Titolo:||Treatment strategies for apatient with rheumatoid arthritis and hepatitis C.|
|Citazione:||Giannitti, C., Bellisai, F., Ferri, C., & Galeazzi, M. (2009). Treatment strategies for apatient with rheumatoid arthritis and hepatitis C. EXPERT OPINION ON PHARMACOTHERAPY, 10(4), 579-587.|
|Appare nelle tipologie:||1.1 Articolo in rivista|
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