Plasma levels and urinary excretion of oxypurines--hypoxanthine and xanthine--were evaluated by reverse-phase high-pressure liquid chromatography in 13 patients affected by gastric tumors and in 19 colorectal tumor-bearing patients. Preliminary results indicate higher values of urinary xanthine and an increase in the xanthine/hypoxanthine ratio in cancer patients. The increase was not generalized to all subjects, and did not appear related either to the stage of the disease or to CEA values. The limits within which the determination of urinary oxypurines can be employed as a tumor marker are discussed.
Lorenzi, M., Vannoni, D., Leoncini, R., Caldarone, R., Marinello, E. (1987). The determination of urinary oxypurines as markers of gastrointestinal tumors. TUMORI, 73(3), 289-294 [10.1177/030089168707300313].
The determination of urinary oxypurines as markers of gastrointestinal tumors
LORENZI, MARCO;VANNONI, DANIELA;LEONCINI, ROBERTO;MARINELLO, ENRICO
1987-01-01
Abstract
Plasma levels and urinary excretion of oxypurines--hypoxanthine and xanthine--were evaluated by reverse-phase high-pressure liquid chromatography in 13 patients affected by gastric tumors and in 19 colorectal tumor-bearing patients. Preliminary results indicate higher values of urinary xanthine and an increase in the xanthine/hypoxanthine ratio in cancer patients. The increase was not generalized to all subjects, and did not appear related either to the stage of the disease or to CEA values. The limits within which the determination of urinary oxypurines can be employed as a tumor marker are discussed.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
https://hdl.handle.net/11365/35515
Attenzione
Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo