Binding features of heroin in whole blood and in blood fractions were delineated by measuring the selective spin-lattice relaxation rates of heroin protons in physiologic conditions. Interaction with some receptor located in the whole human blood or in the human plasma was detected and the apparent binding constant calculated (K = 39 mol-1 dm3). Inferences about molecular dynamics of the bound heroin could be also gained.
Barni Comparini, I., Gaggelli, E., Marchettini, N., Valensin, G. (1986). Binding features of diacetylmorphine (heroin) in whole blood and in blood fractions. BIOPHYSICAL JOURNAL, 48(2), 247-251 [10.1016/S0006-3495(85)83778-4].
Binding features of diacetylmorphine (heroin) in whole blood and in blood fractions
Gaggelli, E.;Marchettini, N.;Valensin, G.
1986-01-01
Abstract
Binding features of heroin in whole blood and in blood fractions were delineated by measuring the selective spin-lattice relaxation rates of heroin protons in physiologic conditions. Interaction with some receptor located in the whole human blood or in the human plasma was detected and the apparent binding constant calculated (K = 39 mol-1 dm3). Inferences about molecular dynamics of the bound heroin could be also gained.
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https://hdl.handle.net/11365/35284
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