A new tandem mass spectrometry (MS/MS) method based on the use of an ion trap mass spectrometer for the identification and quantitation of F2-isoprostanes has been developed. It consists of two solid-phase extractions and two derivation steps followed by gas chromatography/negative ion chemical ionization tandem mass spectrometry (GC/NICI-MS/MS) analysis. This method is highly selective and sensitive and it has been successfully applied to biological samples. Copyright © 2003 John Wiley & Sons, Ltd.
Signorini, C., Comporti, M., Giorgi, G. (2003). Ion trap tandem mass spectrometric determination of F2-isoprostanes. JOURNAL OF MASS SPECTROMETRY, 38(10), 1067-1074 [10.1002/jms.520].
Ion trap tandem mass spectrometric determination of F2-isoprostanes
SIGNORINI, C.;COMPORTI, M.;GIORGI, G.
2003-01-01
Abstract
A new tandem mass spectrometry (MS/MS) method based on the use of an ion trap mass spectrometer for the identification and quantitation of F2-isoprostanes has been developed. It consists of two solid-phase extractions and two derivation steps followed by gas chromatography/negative ion chemical ionization tandem mass spectrometry (GC/NICI-MS/MS) analysis. This method is highly selective and sensitive and it has been successfully applied to biological samples. Copyright © 2003 John Wiley & Sons, Ltd.
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https://hdl.handle.net/11365/3520
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