The cyclic decapeptide gramicidin S has been used as a model biopolymer to test the reliability of a structural method which is based on a relaxation analysis of heteronuclear selective NOEs. The observation of through-the-space dipolar couplings between intra- and inter residue amide protons and carbonyl carbons, perfectly consistent with the well established peptide solution conformation, confirms the effectiveness of this structural approach. As a corollary of the latter, carbonyl carbon resonances are unequivocally assigned. Moreover, a direct experimental proof of a Orn-NH2----Phe C = O hydrogen bonding is here given.
|Titolo:||1H-13C selective NOE studies of the decapeptide gramicidin S.|
|Citazione:||Niccolai, N., Rossi, C., P., M., P., N., & W. A., G. (1984). 1H-13C selective NOE studies of the decapeptide gramicidin S. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 124, 739-744.|
|Appare nelle tipologie:||1.1 Articolo in rivista|
File in questo prodotto: