Aggressive fibromatoses are rare neoplasms originating from fascial and aponeurotic tissues. These tumours have a locally aggressive behaviour, infiltrating the surrounding structures and the neuro-vascular bundles, with consequent pain and functional deficit. Surgery is the treatment of choice, but high local relapse rates, from 39% tp 79% of cases, are reported. Radiotherapy, used either as primary therapy or as an adjuvant to surgery, gives good results in terms of local control of the disease, avoiding major cosmetic and functional sequelae. Systemic therapy is usually reserved for recurrences of aggressive fibromatosis after surgery and radiotherapy, but up to now there are not widely accepted protocols. The Authors report their experience with a case of aggressive fibromatosis of the suvraclavicular fossa, recurring after surgery and adjuvant radiotheray, which has been successfully treated with polichemotherapy.
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|Titolo:||Recurrent aggressive fibromatosis of the suvraclavicular fossa: long term response with chemotherapy|
|Citazione:||Neri, A., Testa, M., Lottini, M., & Carli, A.F. (2003). Recurrent aggressive fibromatosis of the suvraclavicular fossa: long term response with chemotherapy. EUROPEAN JOURNAL OF ONCOLOGY, 8(3), 221-224.|
|Appare nelle tipologie:||1.1 Articolo in rivista|