Aim of this work was the study of ferulic acid/cyclodextrin (CD) association complexes. Ferulic acid (FA) is a compound well-known as antioxidant and photoprotective agent (approved in Japan as sunscreen). Notwithstanding this, it is poorly suited for cosmetic applications because it undergoes functional and organoleptic modifications, when it is exposed to air, UV-light and heat. For this reason we prepared a set of FA/CD complexes with the aim to improve its physico-chemical stability. The inclusion complexes were characterized by differential scanning calorimetry (DSC), X-ray diffraction (XRD), and nuclear magnetic resonance (1H-NMR). The FA/α-CD complex showed the most promising properties (high association constant, high degree of photostability, slower FA release) as sunscreen delivery system. © 2007 Springer Science+Business Media, Inc.

Centini, M., Maggiore, M., Casolaro, M., Andreassi, M., Maffei Facino, R., Anselmi, C. (2007). Cyclodextrins as cosmetic delivery systems. JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY, 57(1-4), 109-112 [10.1007/s10847-006-9212-0].

Cyclodextrins as cosmetic delivery systems

Centini, Marisanna;Casolaro, Mario;Andreassi, Marco;Anselmi, Cecilia
2007-01-01

Abstract

Aim of this work was the study of ferulic acid/cyclodextrin (CD) association complexes. Ferulic acid (FA) is a compound well-known as antioxidant and photoprotective agent (approved in Japan as sunscreen). Notwithstanding this, it is poorly suited for cosmetic applications because it undergoes functional and organoleptic modifications, when it is exposed to air, UV-light and heat. For this reason we prepared a set of FA/CD complexes with the aim to improve its physico-chemical stability. The inclusion complexes were characterized by differential scanning calorimetry (DSC), X-ray diffraction (XRD), and nuclear magnetic resonance (1H-NMR). The FA/α-CD complex showed the most promising properties (high association constant, high degree of photostability, slower FA release) as sunscreen delivery system. © 2007 Springer Science+Business Media, Inc.
2007
Centini, M., Maggiore, M., Casolaro, M., Andreassi, M., Maffei Facino, R., Anselmi, C. (2007). Cyclodextrins as cosmetic delivery systems. JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY, 57(1-4), 109-112 [10.1007/s10847-006-9212-0].
File in questo prodotto:
File Dimensione Formato  
110559_UPLOAD.pdf

non disponibili

Tipologia: Altro materiale allegato
Licenza: NON PUBBLICO - Accesso privato/ristretto
Dimensione 143.01 kB
Formato Adobe PDF
143.01 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11365/3390
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo