The mef(A) gene from a clinical isolate of Streptococcus pneumoniae exhibiting the M-type resistance to macrolides was found to be part of the 7,244-bp chromosomal element Tn1207.1, which contained 8 open reading frames. orf2 encodes a resolvase/invertase, and orf5 is a homolog of the macrolide-streptogramin B resistance gene msr(SA).
Santagati, M., Iannelli, F., Oggioni, M.R., Stefani, S., Pozzi, G. (2000). Characterization of a genetic element carrying the macrolide efflux gene mef(A)in Streptococcus pneumoniae. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 44(9), 2585-2587 [10.1128/AAC.44.9.2585-2587.2000].
Characterization of a genetic element carrying the macrolide efflux gene mef(A)in Streptococcus pneumoniae
IANNELLI F.;POZZI G.
2000-01-01
Abstract
The mef(A) gene from a clinical isolate of Streptococcus pneumoniae exhibiting the M-type resistance to macrolides was found to be part of the 7,244-bp chromosomal element Tn1207.1, which contained 8 open reading frames. orf2 encodes a resolvase/invertase, and orf5 is a homolog of the macrolide-streptogramin B resistance gene msr(SA).
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https://hdl.handle.net/11365/32610
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