Acute graft vs host disease is an uncommon and usually fatal complication of lung transplant for which no effective therapy exists. All 8 patients with grade 3 to 4 acute graft vs host disease after lung transplantation described in literature died within 208 days. We report a patient with grade 3 to 4 acute graft vs host disease after bilateral lung transplantation who was successfully treated with high-dose corticosteroids after basiliximab and extracorporeal photopheresis were unsuccessful.
Fossi, A., Voltolini, L., Filippi, R., Luzzi, L., LAGHI PASINI, F., Marchi, B., et al. (2009). Severe acute graft versus host disease after lung transplant: report of a case successfully treated with high dose corticosteroids. THE JOURNAL OF HEART AND LUNG TRANSPLANTATION, 28(5), 508-510 [10.1016/ j.healun.2009.01.023].
Severe acute graft versus host disease after lung transplant: report of a case successfully treated with high dose corticosteroids
VOLTOLINI L;FILIPPI, RITA;LUZZI L;LAGHI PASINI F;GOTTI G;P. ROTTOLI
2009-01-01
Abstract
Acute graft vs host disease is an uncommon and usually fatal complication of lung transplant for which no effective therapy exists. All 8 patients with grade 3 to 4 acute graft vs host disease after lung transplantation described in literature died within 208 days. We report a patient with grade 3 to 4 acute graft vs host disease after bilateral lung transplantation who was successfully treated with high-dose corticosteroids after basiliximab and extracorporeal photopheresis were unsuccessful.
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https://hdl.handle.net/11365/3253
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