Early gastric cancers (EGC) may be subdivided into 2 groups by means of the use of mitotic index, apoptotic index and cell density: EGCs with high cell turnover and low cell density, which show high cell dissociation and, more frequently, lymph node invasion; EGCs with low cell turnover and high cell density. The same parameters discriminate among intestinal type tumors, when separately considered from diffuse ones. No correlation is noted of these 2 groups with transforming growth factor-alpha, epidermal growth factor receptor and p53 expression, gross type, entity of neoangiogenesis, and submucosal invasion.
Spina, D., Miracco, C., Vindigni, C., Gallorini, M., Presenti, L., Marrelli, D., et al. (1998). Cell kinetic patterns in early gastric cancer. INTERNATIONAL JOURNAL OF ONCOLOGY, 12(4), 883-888 [10.3892/ijo.12.4.883].
Cell kinetic patterns in early gastric cancer
MIRACCO C.;MARRELLI D.;ROVIELLO F.;PINTO E.;TOSI P.
1998-01-01
Abstract
Early gastric cancers (EGC) may be subdivided into 2 groups by means of the use of mitotic index, apoptotic index and cell density: EGCs with high cell turnover and low cell density, which show high cell dissociation and, more frequently, lymph node invasion; EGCs with low cell turnover and high cell density. The same parameters discriminate among intestinal type tumors, when separately considered from diffuse ones. No correlation is noted of these 2 groups with transforming growth factor-alpha, epidermal growth factor receptor and p53 expression, gross type, entity of neoangiogenesis, and submucosal invasion.
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https://hdl.handle.net/11365/31869
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