The results of a multicentre double-blind trial are reported in which α-[4-(1,1-dimethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-1-piperidinebut anol (terfenadine, RMI 9918, Triludan®, Teldane®, resp.) and dexchlorpheniramine were compared with placebo in the treatment of allergic rhinitis. Terfenadine and dexchlorpheniramine were found to be equally effective; but terfenadine produced less drowsiness and was effective in a twice daily dosage.

Melillo, G., D'Amato, G., Zanussi, C., Ortolani, C., Pastorello, E., Loy, M., et al. (1982). A multicentre controlled trial of terfenadine, dexchlorpheniramine, and placebo in allergic rhinitis. ARZNEIMITTEL-FORSCHUNG, 32(9 A), 1202-1203.

A multicentre controlled trial of terfenadine, dexchlorpheniramine, and placebo in allergic rhinitis.

P. Sestini;P. Rottoli
1982

Abstract

The results of a multicentre double-blind trial are reported in which α-[4-(1,1-dimethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-1-piperidinebut anol (terfenadine, RMI 9918, Triludan®, Teldane®, resp.) and dexchlorpheniramine were compared with placebo in the treatment of allergic rhinitis. Terfenadine and dexchlorpheniramine were found to be equally effective; but terfenadine produced less drowsiness and was effective in a twice daily dosage.
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11365/31236
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo