Silylcupration and stannylcupration of 4-acetoxy-2-azetidinones gave the corresponding silyl- and stannyl-β-lactams. The first results on the reactivity of these products with electrophiles are reported: 4-(tributylstannyl)- 2-azetidinone undergoes the palladium catalyzed coupling with electrophiles allowing an "umpolung" acylation of the position 4 of the β-lactam ring. © 1990.

Nativi, C., Ricci, A., Taddei, M. (1990). Synthesis of 4-(trimethylsilyl)-2-azetidinones and 4-(tributylstannyl)-2-azetidinones and Some of Their Applications To Beta-lactam Chemistry. TETRAHEDRON LETTERS, 31(18), 2637-2640 [10.1016/0040-4039(90)80147-E].

Synthesis of 4-(trimethylsilyl)-2-azetidinones and 4-(tributylstannyl)-2-azetidinones and Some of Their Applications To Beta-lactam Chemistry

Taddei, Maurizio
1990-01-01

Abstract

Silylcupration and stannylcupration of 4-acetoxy-2-azetidinones gave the corresponding silyl- and stannyl-β-lactams. The first results on the reactivity of these products with electrophiles are reported: 4-(tributylstannyl)- 2-azetidinone undergoes the palladium catalyzed coupling with electrophiles allowing an "umpolung" acylation of the position 4 of the β-lactam ring. © 1990.
1990
Nativi, C., Ricci, A., Taddei, M. (1990). Synthesis of 4-(trimethylsilyl)-2-azetidinones and 4-(tributylstannyl)-2-azetidinones and Some of Their Applications To Beta-lactam Chemistry. TETRAHEDRON LETTERS, 31(18), 2637-2640 [10.1016/0040-4039(90)80147-E].
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11365/30868
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo