Following the administration of 3,5-3H-L-tyrosine (TYR-3H), brain tyrosine specific activity (S.A.) reaches values similar to those of serum, while, following 3H-L-tryptophan (TRY-3H) injection, serum S.A. remains about twice as high as that of the brain, suggesting that a compartment of serum tryptophan does not exchange with the brain. The AA. conclude that this compartment is tryptophan bound to albumine. © 1977 The Italian Pharmacological Society.
De Montis, M.G., Olianas, M.C., Mulas, G., Tagliamonte, A. (1977). Evidence that only free serum tryptophan exchanges with the brain. PHARMACOLOGICAL RESEARCH COMMUNICATIONS, 9(2), 215-220 [10.1016/S0031-6989(77)80025-8].
Evidence that only free serum tryptophan exchanges with the brain
De Montis, M. G.;Tagliamonte, A.
1977-01-01
Abstract
Following the administration of 3,5-3H-L-tyrosine (TYR-3H), brain tyrosine specific activity (S.A.) reaches values similar to those of serum, while, following 3H-L-tryptophan (TRY-3H) injection, serum S.A. remains about twice as high as that of the brain, suggesting that a compartment of serum tryptophan does not exchange with the brain. The AA. conclude that this compartment is tryptophan bound to albumine. © 1977 The Italian Pharmacological Society.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
https://hdl.handle.net/11365/30739
Attenzione
Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo