Following the administration of 3,5-3H-L-tyrosine (TYR-3H), brain tyrosine specific activity (S.A.) reaches values similar to those of serum, while, following 3H-L-tryptophan (TRY-3H) injection, serum S.A. remains about twice as high as that of the brain, suggesting that a compartment of serum tryptophan does not exchange with the brain. The AA. conclude that this compartment is tryptophan bound to albumine. © 1977 The Italian Pharmacological Society.

De Montis, M.G., Olianas, M.C., Mulas, G., Tagliamonte, A. (1977). Evidence that only free serum tryptophan exchanges with the brain. PHARMACOLOGICAL RESEARCH COMMUNICATIONS, 9(2), 215-220 [10.1016/S0031-6989(77)80025-8].

Evidence that only free serum tryptophan exchanges with the brain

De Montis, M. G.;Tagliamonte, A.
1977-01-01

Abstract

Following the administration of 3,5-3H-L-tyrosine (TYR-3H), brain tyrosine specific activity (S.A.) reaches values similar to those of serum, while, following 3H-L-tryptophan (TRY-3H) injection, serum S.A. remains about twice as high as that of the brain, suggesting that a compartment of serum tryptophan does not exchange with the brain. The AA. conclude that this compartment is tryptophan bound to albumine. © 1977 The Italian Pharmacological Society.
1977
De Montis, M.G., Olianas, M.C., Mulas, G., Tagliamonte, A. (1977). Evidence that only free serum tryptophan exchanges with the brain. PHARMACOLOGICAL RESEARCH COMMUNICATIONS, 9(2), 215-220 [10.1016/S0031-6989(77)80025-8].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11365/30739
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