This study aimed to investigate the associations of body composition and fat distribution with bone mineral density (BMD) in elderly Italian subjects. In 866 women (age 64.2±6.5yr) and 168 men (age 65.1±6.1yr), we measured BMD at lumbar spine, at femur, at the total body, and at the right hand. In all subjects, we also measured sex hormones, 25-hydroxyvitamin D, bone markers, and calcium intake. In both men and women, all body composition parameters had significant positive correlations with BMD at all sites after adjusting for age only; after adjusting also for body weight only lean mass (LM) remained positively associated with BMD at all sites except BMD at lumbar spine. In males, LM was associated with BMD at all sites, whereas android fat was associated with BMD at lumbar spine, at femur, and at whole body. In females, fat mass (FM) was positively and age inversely associated with BMD at all sites, whereas gynoid fat and alkaline phosphatase were inversely associated with BMD at lumbar spine and at femur. In conclusion, the role of LM seems more important in males, whereas in women the role of FM prevails with negative associations between gynoid fat and BMD.

Gonnelli, S., Caffarelli, C., Tanzilli, L., Alessi, C., Tomai Pitinca, M.D., Rossi, S., et al. (2013). The Associations of Body Composition and Fat Distribution With Bone Mineral Density in Elderly Italian Men and Women. JOURNAL OF CLINICAL DENSITOMETRY, 16(2), 168-177 [10.1016/j.jocd.2012.02.013].

The Associations of Body Composition and Fat Distribution With Bone Mineral Density in Elderly Italian Men and Women

Gonnelli, S.;Caffarelli, C.;Tanzilli, L.;Alessi, C.;Tomai Pitinca, M. D.;Rossi, S.;Campagna, M. S.;Nuti, R.
2013-01-01

Abstract

This study aimed to investigate the associations of body composition and fat distribution with bone mineral density (BMD) in elderly Italian subjects. In 866 women (age 64.2±6.5yr) and 168 men (age 65.1±6.1yr), we measured BMD at lumbar spine, at femur, at the total body, and at the right hand. In all subjects, we also measured sex hormones, 25-hydroxyvitamin D, bone markers, and calcium intake. In both men and women, all body composition parameters had significant positive correlations with BMD at all sites after adjusting for age only; after adjusting also for body weight only lean mass (LM) remained positively associated with BMD at all sites except BMD at lumbar spine. In males, LM was associated with BMD at all sites, whereas android fat was associated with BMD at lumbar spine, at femur, and at whole body. In females, fat mass (FM) was positively and age inversely associated with BMD at all sites, whereas gynoid fat and alkaline phosphatase were inversely associated with BMD at lumbar spine and at femur. In conclusion, the role of LM seems more important in males, whereas in women the role of FM prevails with negative associations between gynoid fat and BMD.
2013
Gonnelli, S., Caffarelli, C., Tanzilli, L., Alessi, C., Tomai Pitinca, M.D., Rossi, S., et al. (2013). The Associations of Body Composition and Fat Distribution With Bone Mineral Density in Elderly Italian Men and Women. JOURNAL OF CLINICAL DENSITOMETRY, 16(2), 168-177 [10.1016/j.jocd.2012.02.013].
File in questo prodotto:
File Dimensione Formato  
JClinDensit2012.pdf

non disponibili

Tipologia: Post-print
Licenza: NON PUBBLICO - Accesso privato/ristretto
Dimensione 367.46 kB
Formato Adobe PDF
367.46 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11365/30372
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo