Serum levels of tryptophan (Trp) and 5-hydroxytryptophan (5-HTP) were measured in the mother at birth, by normal delivery or cesarean section, on days 1 and 3 post-partum, and in the cord blood of the fetus-newborns. Decreases in Trp and 5-HTP levels during delivery were noted. Conversely, Trp levels in the cord blood of fetus-newborns were significantly higher than those of their mothers, and 5-HTP levels also showed a tendency to increase , whereas on day 1 post-partum Trp values were lower than those in fetal cord, but higher than those during spontaneous delivery. On day 3 post-partum, serum Trp levels were higher than those during spontaneous delivery, but similar to those on day 1. 5-HTP values tended to decrease with respect to those of day 1. Serum Trp and 5-HTP concentrations decreased significantly on day 1 post-partum after cesarean section, but increased on day 3, demonstrating that maternal Trp was being consumed during delivery. A major release of prolactin in serum on days 1 and 3 post-partum there was in women with normal delivery, revealing a correlation between Trp and prolactin in the first few days after birth, in relation to different conditions of delivery.

Carretti, N., Bertazzo, A., Comai, S., Costa, C.V., Allegri, G., Petraglia, F. (2003). Serum tryptophan and 5-hydroxytryptophan at birth and during post-partum days. In Developments in triptophan and serotonin metabolism (pp.757-760). Cham : SPRINGER INTERNATIONAL PUBLISHING AG [10.1007/978-1-4615-0135-0_90].

Serum tryptophan and 5-hydroxytryptophan at birth and during post-partum days

CARRETTI, N.;PETRAGLIA, F.
2003-01-01

Abstract

Serum levels of tryptophan (Trp) and 5-hydroxytryptophan (5-HTP) were measured in the mother at birth, by normal delivery or cesarean section, on days 1 and 3 post-partum, and in the cord blood of the fetus-newborns. Decreases in Trp and 5-HTP levels during delivery were noted. Conversely, Trp levels in the cord blood of fetus-newborns were significantly higher than those of their mothers, and 5-HTP levels also showed a tendency to increase , whereas on day 1 post-partum Trp values were lower than those in fetal cord, but higher than those during spontaneous delivery. On day 3 post-partum, serum Trp levels were higher than those during spontaneous delivery, but similar to those on day 1. 5-HTP values tended to decrease with respect to those of day 1. Serum Trp and 5-HTP concentrations decreased significantly on day 1 post-partum after cesarean section, but increased on day 3, demonstrating that maternal Trp was being consumed during delivery. A major release of prolactin in serum on days 1 and 3 post-partum there was in women with normal delivery, revealing a correlation between Trp and prolactin in the first few days after birth, in relation to different conditions of delivery.
2003
0-306-47755-6
Carretti, N., Bertazzo, A., Comai, S., Costa, C.V., Allegri, G., Petraglia, F. (2003). Serum tryptophan and 5-hydroxytryptophan at birth and during post-partum days. In Developments in triptophan and serotonin metabolism (pp.757-760). Cham : SPRINGER INTERNATIONAL PUBLISHING AG [10.1007/978-1-4615-0135-0_90].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11365/30157
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