Phospholipids of different origin (egg and soya) and purity were used to prepare liposomes by sonication. Loading of these vesicles was performed by means of two different techniques using a fluorescent lipophilic model molecule. The stability of the aggregated structures was checked by addition of increasing amounts of a surfactant to the liposome dispersion. No remarkable differences were observed in either the stability in regard to surfactant-induced breakage or the loading capacity of liposomes respectively prepared with 99% pure egg phosphatidylcholine or with the vegetable phospholipid, a commercial product that had a much lower purity. The comparison of the two loading methods indicated that incorporation of the model molecule within the vesicle structure was higher when the fluorescent marker was added before sonication.

Memoli, A., Palermiti, L.G., Travagli, V., Alhaique, F. (1993). Liposomes in cosmetics: which kind of phospholipid? Which loading method?. JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS, 44(2), 123-128.

Liposomes in cosmetics: which kind of phospholipid? Which loading method?

Travagli V.;
1993-01-01

Abstract

Phospholipids of different origin (egg and soya) and purity were used to prepare liposomes by sonication. Loading of these vesicles was performed by means of two different techniques using a fluorescent lipophilic model molecule. The stability of the aggregated structures was checked by addition of increasing amounts of a surfactant to the liposome dispersion. No remarkable differences were observed in either the stability in regard to surfactant-induced breakage or the loading capacity of liposomes respectively prepared with 99% pure egg phosphatidylcholine or with the vegetable phospholipid, a commercial product that had a much lower purity. The comparison of the two loading methods indicated that incorporation of the model molecule within the vesicle structure was higher when the fluorescent marker was added before sonication.
1993
Memoli, A., Palermiti, L.G., Travagli, V., Alhaique, F. (1993). Liposomes in cosmetics: which kind of phospholipid? Which loading method?. JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS, 44(2), 123-128.
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11365/30147
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo