Correlation between presence of estradiol receptors and epidemiological and clinical data on breast cancer [Correlazione tra presenza di recettori per l'estradiolo e dati epidemiologici e clinici nel cancro della mammella]

The aim of the study is to find an eventual correlation between the presence of Er receptors and epidemiologic (age, domestic anamnesis, weight, menarca) and clinicist factors (cancerous diameter, linfonodes, first symptoms). The presence of receptors is very important for the start of endocrine therapy. In conclusion we can affirm the absence of correlation between the presence of receptors and the factors we considered. The only exception is about the age of patients; very probably because too little number of patients was considered. On the contrary a correlation was observed between receptors and severity of cancerous receptors in neoplastic tissues was obtained with Poffanelli method using an Ultra-Turrax homogenization followed by a centrifugation at 3800 rpm; the separation was achieved with carbon-dextran.