Modeling breast cancer in the mouse has helped to better define the heterogeneity of human breast cancer. In the recent past, it has become evident that some limitations have restricted the potential benefits that can be achieved with this approach. In this review, we highlight some key points that should be taken into account when the mouse is used, with special emphasis on transgenic models.
Caligiuri, I., Rizzolio, F., Boffo, S., Giordano, A., Toffoli, G. (2012). Critical choices for modeling breast cancer in transgenic mouse models. JOURNAL OF CELLULAR PHYSIOLOGY, 227(8), 2988-2991 [10.1002/jcp.24031].
Critical choices for modeling breast cancer in transgenic mouse models
Giordano, Antonio;
2012-01-01
Abstract
Modeling breast cancer in the mouse has helped to better define the heterogeneity of human breast cancer. In the recent past, it has become evident that some limitations have restricted the potential benefits that can be achieved with this approach. In this review, we highlight some key points that should be taken into account when the mouse is used, with special emphasis on transgenic models.
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https://hdl.handle.net/11365/27866
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