Surface expression of CD27 was evaluated in 75 mature leukemic B-cell neoplasms. All cases other than hairy cell leukemia (HCL) expressed CD27. Intensity was significantly higher in chronic lymphocytic leukemia. Lack of CD27 in 17/17 HCL contrasted with expression of this marker in 5/5 splenic lymphomas with villous lymphocytes. Lack of CD27 is a new distinctive feature of HCL among B-cell malignancies.
Forconi, F., Raspadori, D., Lenoci, M., Lauria, F. (2005). Absence of surface CD27 distinguishes hairy cell leukemia from other leukemic B-cell malignancies. HAEMATOLOGICA, 90(2), 266-268.
Absence of surface CD27 distinguishes hairy cell leukemia from other leukemic B-cell malignancies
Forconi, Francesco;Lauria, Francesco
2005-01-01
Abstract
Surface expression of CD27 was evaluated in 75 mature leukemic B-cell neoplasms. All cases other than hairy cell leukemia (HCL) expressed CD27. Intensity was significantly higher in chronic lymphocytic leukemia. Lack of CD27 in 17/17 HCL contrasted with expression of this marker in 5/5 splenic lymphomas with villous lymphocytes. Lack of CD27 is a new distinctive feature of HCL among B-cell malignancies.
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https://hdl.handle.net/11365/24966
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