The electron microscopical analysis of spermatozoa in two infertile male carriers of a pericentric inversion in one of the chromosomes 9 revealed the presence of a peculiar defect affecting the tails' fibrous sheath in both patients. This structure appeared completely disorganized and hyperplasic; sometimes the defect was associated with other usual malformations concerning the nuclear and acrosomal shape and texture and the axonemal assembly. Most spermatozoa (90-100%) of these patients were immotile. Our findings point to a definite ultrastructural sperm defect found in cases of autosomal inversion.
Baccetti, B., Collodel, G., Crisà, D., Moretti, E., Piomboni, P. (1997). Notulae seminologicae. 8. Ultrastructural sperm defects in two men, carriers of autosomal inversion. ANDROLOGIA, 29(5), 277-282 [10.1111/j.1439-0272.1997.tb00482.x].
Notulae seminologicae. 8. Ultrastructural sperm defects in two men, carriers of autosomal inversion
Baccetti, B.;Collodel, Giulia;Moretti, Elena;Piomboni, Paola
1997-01-01
Abstract
The electron microscopical analysis of spermatozoa in two infertile male carriers of a pericentric inversion in one of the chromosomes 9 revealed the presence of a peculiar defect affecting the tails' fibrous sheath in both patients. This structure appeared completely disorganized and hyperplasic; sometimes the defect was associated with other usual malformations concerning the nuclear and acrosomal shape and texture and the axonemal assembly. Most spermatozoa (90-100%) of these patients were immotile. Our findings point to a definite ultrastructural sperm defect found in cases of autosomal inversion.
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https://hdl.handle.net/11365/23927
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