A sperm defect causing infertility in two brothers is described. The malformation, named the “miniacrosome sperm defect,” occurs in the total sperm population. It involves both the nuclei, which have a roundish apex, and the acrosomes, which are small, located in an apical position on the top of the nucleus, and sometimes ring‐shaped. The midpiece and tail segments are normal, and the sperm are perfectly motile but fail to fertilize zona‐free hamster ova in vitro. In spermatids, the absence of a microtubular manchette and reduction of the Golgi complex are evident. 1991 American Society of Andrology
Baccetti, B., Burrini, A.G., Collodel, G., Piomboni, P., Renieri, T. (1991). A "miniacrosome" sperm defect causing infertility in two brothers. JOURNAL OF ANDROLOGY, 12(2), 104-111 [10.1002/j.1939-4640.1991.tb00225.x].
A "miniacrosome" sperm defect causing infertility in two brothers
Baccetti, B.;Burrini, A. G.;Collodel, G.;Piomboni, P.;Renieri, T.
1991-01-01
Abstract
A sperm defect causing infertility in two brothers is described. The malformation, named the “miniacrosome sperm defect,” occurs in the total sperm population. It involves both the nuclei, which have a roundish apex, and the acrosomes, which are small, located in an apical position on the top of the nucleus, and sometimes ring‐shaped. The midpiece and tail segments are normal, and the sperm are perfectly motile but fail to fertilize zona‐free hamster ova in vitro. In spermatids, the absence of a microtubular manchette and reduction of the Golgi complex are evident. 1991 American Society of Andrology
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https://hdl.handle.net/11365/23926
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